Biofilms: Microbial Life on Surfaces
- R. Donlan
- BiologyEmerging Infectious Diseases
- 1 September 2002
A greater understanding of biofilm processes should lead to novel, effective control strategies for biofilm control and a resulting improvement in patient management.
Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
- R. Donlan, J. Costerton
- Biology, MedicineClinical Microbiology Reviews
- 1 April 2002
It is understood that biofilms are universal, occurring in aquatic and industrial water systems as well as a large number of environments and medical devices relevant for public health, and that treatments may be based on inhibition of genes involved in cell attachment and biofilm formation.
Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017
- S. Berríos-Torres, C. Umscheid, W. Schecter
- MedicineJAMA Surgery
- 1 August 2017
This guideline is intended to provide new and updated evidence-based recommendations for the prevention of SSI and should be incorporated into comprehensive surgical quality improvement programs to improve patient safety.
Biofilms and device-associated infections.
- R. Donlan
- BiologyEmerging Infectious Diseases
- 1 March 2001
To better understand and control biofilms on indwelling medical devices, researchers should develop reliable sampling and measurement techniques, investigate the role of bioFilms in antimicrobial drug resistance, and establish the link between biofilm contamination and patient infection.
Biofilm formation: a clinically relevant microbiological process.
- R. Donlan
- Medicine, BiologyClinical Infectious Diseases
- 15 October 2001
An appreciation of the role of biofilms in infection should enhance the clinical decision-making process.
Bacteriophage Cocktail for the Prevention of Biofilm Formation by Pseudomonas aeruginosa on Catheters in an In Vitro Model System
- Weiling Fu, T. Forster, O. Mayer, John J. Curtin, S. Lehman, R. Donlan
- Biology, MedicineAntimicrobial Agents and Chemotherapy
- 12 October 2009
The potential of applying phages, especially phage cocktails, to the surfaces of indwelling medical devices for mitigating biofilm formation by clinically relevant bacteria is suggested.
Role of biofilms in the survival of Legionella pneumophila in a model potable-water system.
- R. Murga, T. Forster, E. Brown, J. Pruckler, B. Fields, R. Donlan
- BiologyMicrobiology
- 1 November 2001
It was found that, although unable to replicate in the absence of H. vermiformis, L. pneumophila was able to persist, and biofilm matrices, known to provide a habitat and a gradient of nutrients, might allow the survival and multiplication of legionellae outside a host cell.
Using Bacteriophages To Reduce Formation of Catheter-Associated Biofilms by Staphylococcus epidermidis
- John J. Curtin, R. Donlan
- Biology, MedicineAntimicrobial Agents and Chemotherapy
- 1 April 2006
Treatment of hydrogel-coated silicone catheters with an S. epidermidis bacteriophage in an in vitro model system significantly reduced viable biofilm formation by S.EpidermidIS over a 24-h exposure period, suggesting the potential of bacteriophile for mitigating biofilm Formation on indwelling catheter and reducing the incidence of catheter-related infections.
Community-onset methicillin-resistant Staphylococcus aureus associated with antibiotic use and the cytotoxin Panton-Valentine leukocidin during a furunculosis outbreak in rural Alaska.
- H. Baggett, T. Hennessy, J. Butler
- Medicine, BiologyJournal of Infectious Diseases
- 1 May 2004
Selective antibiotic pressure for drug-resistant strains carrying PVL may have led to the emergence and spread of CO-MRSA in rural Alaska.
Preventing biofilms of clinically relevant organisms using bacteriophage.
- R. Donlan
- BiologyTrends in Microbiology
- 1 February 2009
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