• Publications
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Biofilms: Microbial Life on Surfaces
  • R. Donlan
  • Biology, Medicine
  • Emerging infectious diseases
  • 1 September 2002
Microorganisms attach to surfaces and develop biofilms. Biofilm-associated cells can be differentiated from their suspended counterparts by generation of an extracellular polymeric substance (EPS)Expand
  • 2,876
  • 185
Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
SUMMARY Though biofilms were first described by Antonie van Leeuwenhoek, the theory describing the biofilm process was not developed until 1978. We now understand that biofilms are universal,Expand
  • 3,466
  • 83
Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017
Importance The human and financial costs of treating surgical site infections (SSIs) are increasing. The number of surgical procedures performed in the United States continues to rise, and surgicalExpand
  • 693
  • 41
Biofilm formation: a clinically relevant microbiological process.
  • R. Donlan
  • Medicine, Biology
  • Clinical infectious diseases : an official…
  • 15 October 2001
Microorganisms universally attach to surfaces and produce extracellular polysaccharides, resulting in the formation of a biofilm. Biofilms pose a serious problem for public health because of theExpand
  • 881
  • 32
Biofilms and device-associated infections.
  • R. Donlan
  • Medicine
  • Emerging infectious diseases
  • 1 March 2001
Microorganisms commonly attach to living and nonliving surfaces, including those of indwelling medical devices, and form biofilms made up of extracellular polymers. In this state, microorganisms areExpand
  • 1,095
  • 32
Role of biofilms in the survival of Legionella pneumophila in a model potable-water system.
Legionellae can infect and multiply intracellularly in both human phagocytic cells and protozoa. Growth of legionellae in the absence of protozoa has been documented only on complex laboratory media.Expand
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Bacteriophage Cocktail for the Prevention of Biofilm Formation by Pseudomonas aeruginosa on Catheters in an In Vitro Model System
ABSTRACT Microorganisms develop biofilms on indwelling medical devices and are associated with device-related infections, resulting in substantial morbidity and mortality. This study investigated theExpand
  • 259
  • 15
Community-onset methicillin-resistant Staphylococcus aureus associated with antibiotic use and the cytotoxin Panton-Valentine leukocidin during a furunculosis outbreak in rural Alaska.
BACKGROUND Community-onset methicillin-resistant Staphylococcus aureus (CO-MRSA) reports are increasing, and infections often involve soft tissue. During a CO-MRSA skin infection outbreak in Alaska,Expand
  • 259
  • 12
Statistical assessment of a laboratory method for growing biofilms.
Microbial biofilms have been grown in laboratories using a variety of different approaches. A laboratory biofilm reactor system, called the CDC biofilm reactor (CBR) system, has been devised forExpand
  • 206
  • 11
High-Level Vancomycin-Resistant Staphylococcus aureus Isolates Associated with a Polymicrobial Biofilm
ABSTRACT Glycopeptides such as vancomycin are the treatment of choice for infections due to methicillin-resistant Staphylococcus aureus. This study describes the identification of high-levelExpand
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