• Publications
  • Influence
Biofilms: Microbial Life on Surfaces
  • R. Donlan
  • Biology, Medicine
    Emerging infectious diseases
  • 1 September 2002
TLDR
A greater understanding of biofilm processes should lead to novel, effective control strategies for biofilm control and a resulting improvement in patient management.
Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
TLDR
It is understood that biofilms are universal, occurring in aquatic and industrial water systems as well as a large number of environments and medical devices relevant for public health, and that treatments may be based on inhibition of genes involved in cell attachment and biofilm formation.
Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017
TLDR
This guideline is intended to provide new and updated evidence-based recommendations for the prevention of SSI and should be incorporated into comprehensive surgical quality improvement programs to improve patient safety.
Biofilms and device-associated infections.
  • R. Donlan
  • Medicine
    Emerging infectious diseases
  • 1 March 2001
TLDR
To better understand and control biofilms on indwelling medical devices, researchers should develop reliable sampling and measurement techniques, investigate the role of bioFilms in antimicrobial drug resistance, and establish the link between biofilm contamination and patient infection.
Biofilm formation: a clinically relevant microbiological process.
  • R. Donlan
  • Medicine
    Clinical infectious diseases : an official…
  • 15 October 2001
TLDR
An appreciation of the role of biofilms in infection should enhance the clinical decision-making process.
Role of biofilms in the survival of Legionella pneumophila in a model potable-water system.
TLDR
It was found that, although unable to replicate in the absence of H. vermiformis, L. pneumophila was able to persist, and biofilm matrices, known to provide a habitat and a gradient of nutrients, might allow the survival and multiplication of legionellae outside a host cell.
Bacteriophage Cocktail for the Prevention of Biofilm Formation by Pseudomonas aeruginosa on Catheters in an In Vitro Model System
TLDR
The potential of applying phages, especially phage cocktails, to the surfaces of indwelling medical devices for mitigating biofilm formation by clinically relevant bacteria is suggested.
Community-onset methicillin-resistant Staphylococcus aureus associated with antibiotic use and the cytotoxin Panton-Valentine leukocidin during a furunculosis outbreak in rural Alaska.
TLDR
Selective antibiotic pressure for drug-resistant strains carrying PVL may have led to the emergence and spread of CO-MRSA in rural Alaska.
High-Level Vancomycin-Resistant Staphylococcus aureus Isolates Associated with a Polymicrobial Biofilm
TLDR
Multiple combinations of resistance genes among the various isolates of staphylococci and enterococci, including vanA, tet(S), and tet(U), illustrate the dynamic nature of gene acquisition and loss within and between bacterial species throughout the course of infection.
Preventing biofilms of clinically relevant organisms using bacteriophage.
  • R. Donlan
  • Biology, Medicine
    Trends in microbiology
  • 1 February 2009
TLDR
Bacteriophage has been used to treat infectious diseases in humans and there is interest in phage to control biofilms, and Lytic bacteriophages could become a new class of anti-biofilm agents.
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