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A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.
Misfolding and aggregation are associated with cytotoxicity in several protein folding diseases. A large network of molecular chaperones ensures protein quality control. Here, we show that within theExpand
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system
Significance Snake venoms are toxic protein cocktails used for prey capture. To investigate the evolution of these complex biological weapon systems, we sequenced the genome of a venomous snake, theExpand
Primitive Duplicate Hox Clusters in the European Eel's Genome
The enigmatic life cycle and elongated body of the European eel (Anguilla anguilla L., 1758) have long motivated scientific enquiry. Recently, eel research has gained in urgency, as the populationExpand
Comparison of the exomes of common carp (Cyprinus carpio) and zebrafish (Danio rerio).
Research on common carp, Cyprinus carpio, is beneficial for zebrafish research because of resources available owing to its large body size, such as the availability of sufficient organ material forExpand
Urochordate βγ-Crystallin and the Evolutionary Origin of the Vertebrate Eye Lens
A refracting lens is a key component of our image-forming camera eye; however, its evolutionary origin is unknown because precursor structures appear absent in nonvertebrates [1]. The vertebrateExpand
A High-Throughput Screen for Tuberculosis Progression
One-third of the world population is infected with Mycobacterium tuberculosis and multi-drug resistant strains are rapidly evolving. The noticeable absence of a whole organism high-throughputExpand
Multiple Kisspeptin Receptors in Early Osteichthyans Provide New Insights into the Evolution of This Receptor Family
Deorphanization of GPR54 receptor a decade ago led to the characterization of the kisspeptin receptor (Kissr) in mammals and the discovery of its major role in the brain control of reproduction.Expand
Urochordate betagamma-crystallin and the evolutionary origin of the vertebrate eye lens.
A refracting lens is a key component of our image-forming camera eye; however, its evolutionary origin is unknown because precursor structures appear absent in nonvertebrates. The vertebrateExpand
Schooling reduces energy consumption in swimming male European eels, Anguilla anguilla L.
Abstract During migration, swimming in schools provides fish with a number of behavioural and ecological advantages, including increased food supply and reduced predation risk. Previous work showsExpand
Rapid de novo assembly of the European eel genome from nanopore sequencing reads
TLDR
We have sequenced the genome of the endangered European eel using the MinION by Oxford Nanopore, and assembled these data using a novel algorithm specifically designed for large eukaryotic genomes. Expand
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