• Publications
  • Influence
P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite
BackgroundThe NLR family, pyrin domain-containing 3 (NLRP3) inflammasome plays a key role in intracerebral hemorrhage (ICH)-induced inflammatory injury, and the purinergic 2X7 receptor (P2X7R) isExpand
  • 76
  • 12
Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant
BackgroundIntracerebral hemorrhage (ICH) induces potently oxidative stress responses and inflammatory processes. Isoliquiritigenin (ILG) is a flavonoid with a chalcone structure and can activateExpand
  • 74
  • 7
Blood–brain barrier disruption induced by hemoglobin in vivo: Involvement of up-regulation of nitric oxide synthase and peroxynitrite formation
Accumulating evidence has demonstrated that up-regulation of nitric oxide synthase (NOS) and subsequent peroxynitrite (ONOO(-)) formation exert a devastating effect on the damage of BBB in multipleExpand
  • 42
  • 5
Isolation and identification of lipopeptide antibiotics from Paenibacillus elgii B69 with inhibitory activity against methicillin-resistant Staphylococcus aureus
Two lipopeptide antibiotics, pelgipeptins C and D, were isolated from Paenibacillus elgii B69 strain. The molecular masses of the two compounds were both determined to be 1,086 Da. Mass-spectrometry,Expand
  • 36
  • 5
Isolation and partial characterization of antibiotics produced by Paenibacillus elgii B69.
A newly isolated strain B69 with broad antimicrobial activity was identified as Paenibacillus elgii by 16S rRNA gene sequence analysis, along with physiological and biochemical characterization. TwoExpand
  • 45
  • 4
[Interaction between polymorphisms in NQO1(C609T) and XRCC1(G28152A) and their correlation with smoking on gastric cancer].
OBJECTIVE To investigate the relationship between polymorphism of NAD(P)H quinone oxidoreductase 1 (NQO1) and X-ray repair cross-complementing group1 (XRCC1) and their correlation with smoking on theExpand
  • 7
  • 2
Facile and large-scale chemical synthesis of highly porous secondary submicron/micron-sized NiCo2O4 materials for high-performance aqueous hybrid AC-NiCo2O4 electrochemical capacitors
Highly porous nickel cobaltite (NiCo2O4) materials have been synthesized via a facile and scalable chemical synthesis route. The obtained NiCo2O4 material displays a typical secondaryExpand
  • 176
  • 1
Modification of cut-off values for HE4, CA125 and the ROMA algorithm for early-stage epithelial ovarian cancer detection: Results from 1021 cases in South China.
OBJECTIVES The purpose of this study was to evaluate the performance of human epididymis protein 4 (HE4) and the Risk of Ovarian Malignancy Algorithm (ROMA) in early stage epithelial ovarian cancerExpand
  • 16
  • 1
Long noncoding RNA MRAK009713 is a novel regulator of neuropathic pain in rats
Abstract Long noncoding RNAs have been implicated in neuropathy. Here, we identify and validate a long noncoding RNA, MRAK009713, as the primary regulator of neuropathic pain in chronic constrictionExpand
  • 27
  • 1