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Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT SPECT imaging: the [123I]-FP-CIT study group.
TLDR
Visual assessment of [123I]-FP-CIT SPECT images is an easily applied diagnostic test which is helpful in the differential diagnosis of tremor disorders and in confirming a clinical diagnosis of a hypokinetic-rigid syndrome. Expand
PET visualization of microglia in multiple sclerosis patients using [11C]PK11195
TLDR
[11C]PK11195 and PET are able to demonstrate inflammatory processes with microglial involvement in MS, and an increase of normal‐appearing white matter (NAWM) uptake was found, propagating NAWM as the possible real burden of disease. Expand
Apoptosis-detecting radioligands: current state of the art and future perspectives
TLDR
Major emphasis is placed on the group of Annexin V-based radioligands, in particular 99mTc-Hynic-Annexin V, since this molecule is by far the most extensively investigated and best-characterised apoptosis marker at present. Expand
Regional Brain Activity during Different Paradigms of Mental Rotation in Healthy Volunteers: A Positron Emission Tomography Study
TLDR
PET was used to observe changes in regional cerebral blood flow in 10 right-handed healthy volunteers performing two paradigms of mental rotation and revealed that the left gyrus precentralis was activated significantly during the alphanumeric condition and that theleft gyrus lingualis was significantly activated during the paired figures condition. Expand
Molecular imaging of hypoxia with radiolabelled agents
TLDR
This review aims to give a detailed overview of non-invasive molecular imaging modalities with radiolabelled PET and SPECT tracers that are available to measure tumour hypoxia. Expand
Value of 11C-methionine PET in imaging brain tumours and metastases
TLDR
The role of MET PET in imaging cerebral gliomas, the most popular amino acid tracer used in PET imaging of brain tumours, and other nuclear imaging possibilities in brain tumour imaging are reviewed. Expand
Optimised tracer-dependent dosage cards to obtain weight-independent effective doses
TLDR
Using the EANM factors for tracers belonging to clusters B and C results in significantly higher effective doses to children, and is suggested using three tracer-dependent dosage cards for which the correction factors have been calculated to obtain weight-independent effective doses. Expand
Prefrontal 5-HT2a receptor binding index, hopelessness and personality characteristics in attempted suicide.
TLDR
Lower central serotonergic function, hopelessness and harm avoidance are interrelated phenomena, which may increase the probability of the occurrence of attempted suicide. Expand
SPECT neuropsychological activation procedure with the Verbal Fluency Test in attempted suicide patients
TLDR
These findings indicate a blunted increase in prefrontal blood perfusion as a possible biological reason for reduced drive and loss of initiative in attempted suicide patients. Expand
Technetium-99m RP527, a GRP analogue for visualisation of GRP receptor-expressing malignancies: a feasibility study
TLDR
The data presented suggest that 99mTc-RP527 results in specific tumour localisation and exhibits good imaging characteristics with a good T/N ratio that may be further enhanced by single-photon emission tomography. Expand
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