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Adipokines oversecreted by omental adipose tissue in human obesity.
TLDR
Six adipokines were newly identified as oversecreted by OAT in obesity, which may link obesity to its cardiovascular or metabolic comorbidities. Expand
Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue.
TLDR
Production of ApN and regulation of its related gene (apM1) have not yet been studied in human visceral adipose tissue and regulation could contribute to the decreased apM1/ApN levels in insulin-resistant patients with obesity and the Metabolic Syndrome. Expand
Multihormonal control of ob gene expression and leptin secretion from cultured human visceral adipose tissue: increased responsiveness to glucocorticoids in obesity.
TLDR
Gl glucocorticoids, at physiological concentrations, stimulated leptin secretion by enhancing the pretranslational machinery in human visceral fat by inhibiting the dexamethasone-induced rise in ob mRNA and leptin release. Expand
In vitro hyperresponsiveness to tumor necrosis factor-alpha contributes to adipokine dysregulation in omental adipocytes of obese subjects.
TLDR
In obesity, TNF-alpha that is [corrected] over other SVC-secreted factors, a crucial determinant of adipokine dysregulation acts on enlarged adipocytes, which are hyperresponsive to this triggering signal. Expand
Acute localized diverticulitis: Optimum management requires accurate staging
TLDR
It is concluded that accurate classification of the disease is essential, and most patients who develop an acute phlegmonous diverticulitis do well with conservative treatment, and prophylactic resection is not indicated. Expand
In Vitro Hyperresponsiveness to Tumor Necrosis Factor-α Contributes to Adipokine Dysregulation in Omental Adipocytes of Obese Subjects
TLDR
Adipocytes of obese subjects mainly overexpressed adipokines, in comparison with those of lean ones, when cultured in SVC-conditioned media, indicating that among the numerous factors secreted by SVCs, TNF is a crucial contributor to adipokine dysregulation. Expand
Hormonal control of plasminogen activator inhibitor-1 gene expression and production in human adipose tissue: stimulation by glucocorticoids and inhibition by catecholamines.
TLDR
Evidence is provided for a reciprocal regulation of PAI-1 by dexamethasone (positive effector) and cAMP/catecholamines (negative effectors) in cultured human adipose tissue and thereby be a link between this disorder and cardiovascular disease. Expand
Inadequate detection of accessory spleens and splenosis with laparoscopic splenectomy
TLDR
This prospective clinical study suggests that elective laparoscopic surgery for hematological diseases does not allow complete detection of accessory spleens and residual splenic tissue is detectable in half of the patients during the follow-up. Expand
FDG-PET improves the staging and selection of patients with recurrent colorectal cancer
TLDR
It is concluded that whole-body FDG-PET is highly sensitive for both the diagnosis and the staging of patients with recurrent colorectal cancer and its use in conjunction with conventional imaging procedures results in a more accurate selection of patients for surgical treatment with curative intent. Expand
Preoperative lymph node staging in rectal cancer: a difficult challenge
TLDR
It is concluded that a low percentage of LNs are detected by EUS in the experience and it seems difficult to reliably correlate metastatic invasion with a specific endosonic appearance. Expand
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