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The Gut of Geographically Disparate Ciona intestinalis Harbors a Core Microbiota
- Larry J Dishaw, Jaime A. Flores-Torres, J. Gilbert
- Biology, Environmental SciencePloS one
- 2 April 2014
It is shown that the Ciona gut not only is colonized by a complex community of bacteria, but also that samples from three geographically isolated populations reveal striking similarity in abundant operational taxonomic units (OTUs) consistent with the selection of a core community by the gut ecosystem.
Immunoglobulin superfamily receptors in protochordates: before RAG time
Urochordates and cephalochordates do not have an adaptive immune system involving the somatic rearrangement of their antigen receptor genes, and the status of their genes reflects perhaps a primitive pre‐recombination‐activating gene (RAG) stage that could suggest the pathway leading to the genesis of the T‐cell receptor (TCR) and antibodies.
CiC3-1a-Mediated Chemotaxis in the Deuterostome Invertebrate Ciona intestinalis (Urochordata) 1
Findings indicate that CiC3-1a mediates chemotaxis of C. intestinalis hemocytes, thus suggesting an important role for this molecule in inflammatory processes.
A role for variable region-containing chitin-binding proteins (VCBPs) in host gut–bacteria interactions
- Larry J Dishaw, S. Giacomelli, M. Pinto
- BiologyProceedings of the National Academy of Sciences
- 19 September 2011
Various aspects of VCBP expression and function suggest an early origin for the key elements that are central to the dialogue between the immune system of the host and gut microflora.
Complement in urochordates: cloning and characterization of two C3-like genes in the ascidian Ciona intestinalis
The isolation of two C3-like genes, CiC3-1 and CiC 3-2, from blood cell total RNA of the ascidian Ciona intestinalis are reported, showing an overall similarity to the other C3 molecules already characterized.
Gamete self‐discrimination in ascidians: A role for the follicle cells
It is shown for the first time that self‐discrimination, which occurs on the egg vitelline coat, is established there in late oogenesis and is contributed or controlled by products of the overlying follicle cells.
A study of the chorion and the follicle cells in relation to the sperm-egg interaction in the ascidian, Ciona intestinalis.
Store-operated calcium channel regulates the chemotactic behavior of ascidian sperm
- Manabu Yoshida, Makiko Ishikawa, H. Izumi, R. De Santis, M. Morisawa
- BiologyProceedings of the National Academy of Sciences…
- 23 December 2002
Modulators of the store-operated Ca2+ channel, SK&F96365, Ni2+, 2-aminoethoxydiphenylborane, and thapsigargin inhibit the chemotactic behavior of the ascidian sperm; on the other hand, blockers of voltage-dependent Ca2- channels did not inhibit theChemotaxis.
Ca2+ and Na+ current patterns during oocyte maturation, fertilization, and early developmental stages of Ciona intestinalis
- A. Cuomo, F. Silvestre, R. De Santis, E. Tosti
- BiologyMolecular reproduction and development
- 1 April 2006
An involvement of L‐type Ca2+ currents in meiotic progression from the GV to MI stage is implied and a major role of plasma membrane permeability and a minor function of specific currents during initial cell line segregation events are inferred.
Gut immunity in a protochordate involves a secreted immunoglobulin-type mediator binding host chitin and bacteria
It is shown that the gut mucosa of Ciona intestinalis contains an extensive matrix of chitin fibrils to which VCBPs bind early in gut development, before feeding.