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The Gut of Geographically Disparate Ciona intestinalis Harbors a Core Microbiota
It is now widely understood that all animals engage in complex interactions with bacteria (or microbes) throughout their various life stages. This ancient exchange can involve cooperation and hasExpand
CiC3-1a-Mediated Chemotaxis in the Deuterostome Invertebrate Ciona intestinalis (Urochordata) 1
Deuterostome invertebrates possess complement genes, and in limited instances complement-mediated functions have been reported in these organisms. However, the organization of the complementExpand
A role for variable region-containing chitin-binding proteins (VCBPs) in host gut–bacteria interactions
A number of different classes of molecules function as structural matrices for effecting innate and adaptive immunity. The most extensively characterized mediators of adaptive immunity are theExpand
Immunoglobulin superfamily receptors in protochordates: before RAG time
Summary:  Urochordates and cephalochordates do not have an adaptive immune system involving the somatic rearrangement of their antigen receptor genes. They do not have antigen‐presenting molecules ofExpand
Complement in urochordates: cloning and characterization of two C3-like genes in the ascidian Ciona intestinalis
The recent identification of complement components in deuterostome invertebrates has indicated the presence of a complement system operating via an alternative pathway in echinoderms and tunicatesExpand
A study of the chorion and the follicle cells in relation to the sperm-egg interaction in the ascidian, Ciona intestinalis.
Abstract We present ultrastructural observations on the processes underlying interaction between the spermatozoon and the egg envelopes in Ciona intestinalis. The morphological and cytochemical basisExpand
Store-operated calcium channel regulates the chemotactic behavior of ascidian sperm
The sperm-activating and -attracting factor released from the eggs of the ascidians Ciona intestinalis and Ciona savignyi requires extracellular Ca2+ for activating sperm motility and elicitingExpand
Gamete self‐discrimination in ascidians: A role for the follicle cells
Gamete self‐incompatibility in the hermaphrodite tunicate Ciona intestinalis is a useful system with which to study self‐nonself recognition. We have used in vitro fertilization of oocytes isolatedExpand
First Identification of a Chemotactic Receptor in an Invertebrate Species: Structural and Functional Characterization of Ciona intestinalis C3a Receptor
In mammals, the bioactive fragment C3a, released from C3 during complement activation, is a potent mediator of inflammatory reactions and exerts its functional activity through the specific bindingExpand
Ca2+ and Na+ current patterns during oocyte maturation, fertilization, and early developmental stages of Ciona intestinalis
Using the whole‐cell voltage clamp technique, the electrical changes in oocyte and embryo plasma membrane were followed during different meiotic and developmental stages in Ciona intestinalis. WeExpand
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