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Numerical simulation of the North Atlantic Ocean at 1/10 degrees
Abstract In this paper an initial analysis of an 0.1° simulation of the North Atlantic Ocean using a level-coordinate ocean general circulation model forced with realistic winds covering the periodExpand
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Activated ClpP kills persisters and eradicates a chronic biofilm infection
Chronic infections are difficult to treat with antibiotics but are caused primarily by drug-sensitive pathogens. Dormant persister cells that are tolerant to killing by antibiotics are responsibleExpand
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New mass spectrometric methods for the study of noncovalent associations of biopolymers
The use of electrospray ionization–mass spectrometry(ESI–MS) for the characterization of noncovalent complexes of biomacromolecules in solution is based upon the gentle nature of the electrosprayExpand
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Separation and chemical characterization of finely-sized fly-ash particles
The concentrations of 43 major, minor, and trace elements were measured by x-ray fluorescence, atomic absorption, and instrumental neutron activation for nine well-defined size fractions, with massExpand
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Using Electrospray Ionization FTICR Mass Spectrometry To Study Competitive Binding of Inhibitors to Carbonic Anhydrase
We report a method based on mass spectrometry for the characterization of noncovalent complexes of proteins with mixtures of ligands; this method is relevant to the study of drug leads and may beExpand
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Capillary zone electrophoresis-MS
Coupling the separation capabilities of capillary zone electrophoresis with the analytical specificity of mass spectrometry yields a tool for detecting levels of substances down to 10 attomoles.
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Trapping, detection and reaction of very large single molecular ions by mass spectrometry
RECENT developments have made electrospray-ionization (ESI) mass spectrometry1–3 an important technique for measuring molecular weights and studying the structures of large molecules of relativeExpand
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Isotopic beat patterns in Fourier transform ion cyclotron resonance mass spectrometry: implications for high resolution mass measurements of large biopolymers
Abstract Fourier trasform ion cyclotron resonance (FTICR) mass spectrometry time domain signals from multiply charged biopolymer ions exhibit characteristics and predictable beat patterns due to theExpand
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Attomole level capillary electrophoresis-mass spectrometric protein analysis using 5 .mu.m i.d. capillaries
In this correspondence the authors report the use of chemically modified 5-[mu]-i.d. capillaries for CE-MS of proteins. The authors have found that the use of small inner diameter capillaries resultsExpand
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Mass spectrometric characterization of sequence-specific complexes of DNA and transcription factor PU.1 DNA binding domain.
Electrospray ionization mass spectrometry (ESI-MS) has been used to study the noncovalent interaction of the 13.5-kDa DNA binding domain of PU.1 (PU.1-DBD) with specific double-stranded DNA (dsDNA)Expand
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