• Publications
  • Influence
Relaxometry of brain: Why white matter appears bright in MRI
The remarkable success of magnetic resonance imaging of adult brain relates to the unusually large ratio of the longitudinal relaxation rates 1 / T1 of white and gray matter, ∼2:1 at physiologicalExpand
  • 252
  • 13
Mass culture of hydra: an improved method and its application to other aquatic invertebrates
Virtually unlimited numbers of hydra can be grown under precise conditions in the laboratory with relative ease. Artemia cysts must be treated to remove gross contamination before hatching theExpand
  • 191
  • 9
Magnetic field dependence of 1/T1 of protons in tissue.
It is well established that the spin-lattice magnetic relaxation rate 1/T1 of solvent protons in homogeneous protein solutions increases dramatically as the magnetic field is reduced well below theExpand
  • 151
  • 3
Conformation as the determinant of saccharide binding in concanavalin A: Ca2+-concanavalin A complexes.
The existence of two conformational states of concanavalin A (Con A) with different metal ion binding properties has been recently demonstrated (Brown, R. D., Brewer, C. F., & Koenig, S. H. (1977)Expand
  • 47
  • 3
Relaxation of water protons in the intra‐ and extracellular regions of blood containing Gd(DTPA)
The magnetic field dependence of the longitudinal relaxation rates 1/T1 (NMRD profiles) of blood and plasma from rabbits before and after injection of Gd(DTPA) are reported as a function of magneticExpand
  • 107
  • 3
Stoichiometry of manganese and calcium ion binding to concanavalin A.
Using measurements of solvent nuclear (proton) magnetic relaxation dispersion (NMRD), we have previously shown that concanavalin A (Con A) can exist in two conformational forms and that, in theExpand
  • 34
  • 3
Relaxation of solvent protons by paramagnetic ions and its dependence on magnetic field and chemical environment: implications for NMR imaging.
Paramagnetic ions have been used to alter the magnetic relaxation rates 1/T1 and 1/T2 of solvent water protons since the first observations of a proton resonance signal almost four decades ago. TheExpand
  • 33
  • 3
A unified view of relaxation in protein solutions and tissue, including hydration and magnetization transfer
Protein in water solution increases magnetic relaxation rates of solvent nuclei to an extent that depends on magnetic field strength and molecular weight. Koenig and Schillinger (J. Biol. Chem. 244,Expand
  • 98
  • 2