R. Csuk

Publications227
h-index25
Citations2,331
Highly Influential Citations37
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The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis
Triterpenoids are widespread bioactive plant defence compounds with potential use as pharmaceuticals, pesticides and other high-value products. Enzymes belonging to the cytochrome P450 family have an… Expand
  • 55
  • 5
Towards cytotoxic and selective derivatives of maslinic acid.
Several novel esters and amides of maslinic acid were prepared. Their evaluation for cytotoxic activity with a panel of human cancer cell lines using a sulforhodamine B (SRB) assay revealed for some… Expand
  • 56
  • 3
Synthesis and antimicrobial activity of (E) stilbene derivatives.
Plants use multiple defence mechanisms comprising both constitutive and inducible barriers to prevent entering of phytopathogenic micro-organisms. In many plant species one of the most efficient… Expand
  • 54
  • 2
Monitoring the Phase Formation of Coevaporated Lead Halide Perovskite Thin Films by in Situ X-ray Diffraction.
Perovskite solar cells based on (CH3NH3)Pb(I,Cl)3 have recently demonstrated rapidly increasing cell efficiencies. Here, we show progress identifying phases present during the growth of… Expand
  • 70
  • 2
A fruitful decade from 2005 to 2014 for anthraquinone patents
Introduction: Anthraquinones are aromatic compounds whose structures are related to anthracene (parent structure: 9,10-dioxoanthracene) for which various methods for their synthesis have been… Expand
  • 16
  • 2
Betulinic acid and its derivatives: a patent review (2008 – 2013)
  • R. Csuk
  • Chemistry, Medicine
  • Expert opinion on therapeutic patents
  • 18 July 2014
Introduction: Betulinic acid (BA) is a triterpenoid that can be obtained from renewable resources. BA is cytotoxic to many human tumor cell lines mainly by apoptosis but cell death might also be… Expand
  • 89
  • 1
Synthesis and antitumour activity of glycyrrhetinic acid derivatives.
  • S. Schwarz, R. Csuk
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry
  • 1 November 2010
Glycyrrhetinic acid (GA) is one of many interesting triterpenoic acids showing anticancerogenic potential. GA is known to trigger apoptosis in tumour cell lines, although GA has a low cytotoxicity.… Expand
  • 54
  • 1
Oxidative transformations of betulinol
Starting from commercially available betulinol by a combination of several selective oxidation procedures betutinal, betulinic acid, betulonal as well as betulonic acid were obtained in high yields… Expand
  • 40
  • 1
Amino derivatives of glycyrrhetinic acid as potential inhibitors of cholinesterases.
The development of remedies against the Alzheimer's disease (AD) is one of the biggest challenges in medicinal chemistry nowadays. Although not completely understood, there are several strategies… Expand
  • 31
  • 1
Synthesis and antitumor activity of ring A modified glycyrrhetinic acid derivatives.
Triterpenoic acids show many pharmacological effects, among them an antiinflammatory or an antitumor activity. One of these, glycyrrhetinic acid (1) is of interest because of its antitumor profile.… Expand
  • 53
  • 1
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