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- Publications
- Influence
Prediagnostic Leptin, Adiponectin, C-Reactive Protein, and the Risk of Postmenopausal Breast Cancer
- N. Ollberding, Y. Kim, +9 authors M. Goodman
- Medicine
- Cancer Prevention Research
- 1 March 2013
Obesity has been associated with an increased risk of postmenopausal breast cancer. Adipokines and systemic inflammation have been hypothesized to underlie this association. In a case–control study… Expand
Recombinant Human Interleukin 1 Receptor Antagonist in the Treatment of Patients With Sepsis Syndrome: Results From a Randomized, Double-blind, Placebo-Controlled Trial
- C. Fisher, J. Dhainaut, +213 authors D. Stablein
- Medicine
- 15 June 1994
Objective. —To further define the safety and efficacy of recombinant human interleukin 1 receptor antagonist (rhIL-1ra) in the treatment of sepsis syndrome. Study Design. —Randomized, double-blind,… Expand
Dietary fat and prostate cancer: current status.
- L. Kolonel, A. Nomura, R. Cooney
- Medicine
- Journal of the National Cancer Institute
- 3 March 1999
Efforts to elucidate the causes of prostate cancer have met with little success to date. All that is known with certainty is that the incidence increases exponentially with age, varies by geography… Expand
Non-Hodgkin Lymphoma and Circulating Markers of Inflammation and Adiposity in a Nested Case–Control Study: The Multiethnic Cohort
- S. Conroy, G. Maskarinec, +8 authors L. Kolonel
- Medicine
- Cancer Epidemiology, Biomarkers & Prevention
- 8 January 2013
Background: Because immune dysfunction is thought to underlie the development of non-Hodgkin lymphoma (NHL), obesity and chronic inflammation may be involved in its etiology. We examined the… Expand
Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer chemopreventive action.
- L. Zhang, R. Cooney, J. Bertram
- Biology, Medicine
- Carcinogenesis
- 1 November 1991
We have previously demonstrated that diverse carotenoids inhibit chemically induced neoplastic transformation in 10T1/2 cells. To address their mechanism of action, the effects of six diverse… Expand
Diverse carotenoids protect against chemically induced neoplastic transformation.
- J. Bertram, A. Pung, M. Churley, T. J. Kappock, L. Wilkins, R. Cooney
- Biology, Medicine
- Carcinogenesis
- 1 April 1991
The ability of diverse carotenoid to inhibit methylcholanthrene-induced transformation of 10T1/2 cells has been investigated. When delivered using tetrahydrofuran as a novel solvent, all carotenoids… Expand
Gamma-tocopherol detoxification of nitrogen dioxide: superiority to alpha-tocopherol.
- R. Cooney, A. Franke, P. Harwood, V. Hatch-Pigott, L. Custer, L. Mordan
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 1 March 1993
In the vitamin E group, alpha-tocopherol is generally considered to be the most potent antioxidant with the highest vitamin bioactivity, yet gamma-tocopherol is produced in greater amounts by many… Expand
Seasonal variations in plasma micronutrients and antioxidants.
- R. Cooney, A. Franke, +4 authors L. Le Marchand
- Biology, Medicine
- Cancer epidemiology, biomarkers & prevention : a…
- 1 April 1995
Plasma samples were collected at monthly intervals for a period of 1 year from a group of healthy nonsmoking men and women (n = 21) living in Honolulu, HI. Analysis of plasma cholesterol and… Expand
The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain.
- K. Williamson, S. Gabbita, +8 authors K. Hensley
- Medicine
- Nitric oxide : biology and chemistry
- 2002
Oxidative stress and quasi-inflammatory processes recently have been recognized as contributing factors in the pathogenesis of Alzheimer's disease (AD). Reactive nitrating species have specifically… Expand
The Nitration Product 5-Nitro-γ-tocopherol Is Increased in the Alzheimer Brain
- K. Williamson, S. Gabbita, +8 authors K. Hensley
- Chemistry
- 1 March 2002
Abstract Oxidative stress and quasi-inflammatory processes recently have been recognized as contributing factors in the pathogenesis of Alzheimer's disease (AD). Reactive nitrating species have… Expand