Share This Author
Dietary fat and prostate cancer: current status.
It is concluded that dietary fat may indeed be related to prostate cancer risk, although the specific fat components that are responsible are not yet clear.
Prediagnostic Leptin, Adiponectin, C-Reactive Protein, and the Risk of Postmenopausal Breast Cancer
The data suggest that adipokines and systemic inflammation may be associated with the risk of postmenopausal breast cancer independently of BMI, and further prospective studies examining the role of adipokine and inflammatory processes in the etiology of post menopausal breast cancers are warranted.
Diverse carotenoids protect against chemically induced neoplastic transformation.
- J. Bertram, A. Pung, M. Churley, T. J. Kappock, L. Wilkins, R. Cooney
- Biology, ChemistryCarcinogenesis
- 1 April 1991
It is suggested that the most potent carotenoids tested all have the potential for conversion to retinoids (though this has never been demonstrated in mammals for canthaxanthin), and these compounds have two components to their action; one related to their antioxidant properties, the other to their pro-vitamin A activities.
Association of selenium, tocopherols, carotenoids, retinol, and 15-isoprostane F2t in serum or urine with prostate cancer risk: the multiethnic cohort
There was no overall association of serum concentrations of antioxidants and urinary concentrations of 15-isoprostane F2t with risk of prostate cancer or risk of advanced prostate cancer, but there was an inverse association for serum selenium only among African-American men.
Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer chemopreventive action.
Junctional communication appears to play an important role in cell growth control and carcinogenesis, and it is proposed that in this system carotenoid-enhanced intercellular communication provides a mechanistic basis for the cancer chemopreventive action ofcarotenoids.
Gamma-tocopherol detoxification of nitrogen dioxide: superiority to alpha-tocopherol.
- R. Cooney, A. Franke, P. Harwood, V. Hatch-Pigott, L. Custer, L. Mordan
- BiologyProceedings of the National Academy of Sciences…
- 1 March 1993
A fundamental difference in the chemical reactivities of alpha-tocopherol and gamma-tociperol with nitrogen dioxide (NO2), which leads to the formation of a nitrosating agent from alpha-tropopherol, but not from gamma-ocopherol is described, which suggests the superiority of gamma-ococopherol in a mammalian biological assay and a role for endogenous NO production in promotion of neoplastic transformation.
Ethnic differences in serum adipokine and C-reactive protein levels: the multiethnic cohort
ethnic variations in circulating adipokine and CRP levels before and after adjustment for BMI demonstrate the ethnic variations in adiposity in relation to disparities in obesity-related disease risk.
Plasma 25-hydroxyvitamin D3 is associated with decreased risk of postmenopausal breast cancer in whites: a nested case–control study in the multiethnic cohort study
Circulating 25( OH)D3 and 25(OH)D were associated with a reduced risk of postmenopausal breast cancer among whites, but not in other ethnic groups, who reside in low latitude regions.
Seasonal variations in plasma micronutrients and antioxidants.
- R. Cooney, A. Franke, L. Le Marchand
- Biology, MedicineCancer epidemiology, biomarkers & prevention : a…
- 1 April 1995
Assessment by a diet history of food and supplement intake of micronutrients and phytochemicals for 1 year showed good agreement with 1-year mean plasma levels for most carotenoids, vitamin C, and alpha-tocopherol.