R. Cooks

Publications525
h-index79
Citations21,523
Highly Influential Citations271
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Quadrupole ion trap mass spectrometry
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Ambient Mass Spectrometry
TLDR
Desorption electrospray ionization (DESI), the principal method described here, electrically charged droplets are directed at the ambient object of interest; they release ions from the surface, which are then vacuumed through the air into a conventional mass spectrometer.
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Tissue imaging at atmospheric pressure using desorption electrospray ionization (DESI) mass spectrometry.
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Introduction to Organic Spectroscopy
Desorption electrospray ionization mass spectrometry for high-throughput analysis of pharmaceutical samples in the ambient environment.
TLDR
Positive and negative ion DESI are used to characterize the active ingredients in pharmaceutical samples formulated as tablets, ointments, and liquids, and carryover effects are minimized in high-throughput on-line analysis of pharmaceutical samples.
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Development of capabilities for imaging mass spectrometry under ambient conditions with desorption electrospray ionization (DESI)
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In situ trace detection of peroxide explosives by desorption electrospray ionization and desorption atmospheric pressure chemical ionization.
TLDR
Density functional theory (DFT) calculations support the suggested fragmentation mechanisms for the complexes and allowed the rapid detection of peroxide explosives in complex matrixes such as diesel fuel and lubricants using single or multiple cation additives (Na(+, K(+), and Li(+) and NH4(+)) in the spray solvent.
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Mass spectrometry imaging under ambient conditions.
TLDR
The role of bioinformatics in acquiring and interpreting the chemical and spatial information obtained through MSI, especially in biological applications for tissue diagnostic purposes is described, and the challenges in ambient MSI are discussed.
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Instrumentation, applications, and energy deposition in quadrupole ion-trap tandem mass spectrometry
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Latent Fingerprint Chemical Imaging by Mass Spectrometry
TLDR
This work used desorption electrospray ionization mass spectrometry in an imaging mode to record compound-specific chemical fingerprints for Latent fingerprints.
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