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Intramuscular versus intravenous therapy for prehospital status epilepticus.
TLDR
For subjects in status epilepticus, intramuscular midazolam is at least as safe and effective as intravenous lorazepam for prehospital seizure cessation.
Skeletal muscle strength as a predictor of all-cause mortality in healthy men.
TLDR
Survival analysis examined the impact of grip strength and rate of change in strength on all-cause mortality over 40 years and found that in men <60 years, rate of loss of strength was more important than the actual levels, which persisted when muscle mass was considered.
Age-associated loss of power and strength in the upper extremities in women and men.
TLDR
Cross-sectional and longitudinal age-associated reductions in power and isometric strength are described for the upper extremities and the differences between power and strength changes with age in men argue for the importance of factors other than strength affecting power.
Clopidogrel and Aspirin in Acute Ischemic Stroke and High‐Risk TIA
TLDR
In patients with minor isChemic stroke or high‐risk TIA, those who received a combination of clopidogrel and aspirin had a lower risk of major ischemic events but a higher risk ofMajor hemorrhage at 90 days than those who receive aspirin alone.
Muscle quality and age: cross-sectional and longitudinal comparisons.
TLDR
The relationship between muscle quality and age is dependent on how muscle mass is estimated and on whether subjects are studied cross-sectionally or longitudinally.
Pioglitazone after Ischemic Stroke or Transient Ischemic Attack.
TLDR
In this trial involving patients without diabetes who had insulin resistance along with a recent history of ischemic stroke or TIA, the risk of stroke or myocardial infarction was lower among patients who received pioglitazone than among those who received placebo.
Randomized Trial of Thymectomy in Myasthenia Gravis.
TLDR
Thymectomy improved clinical outcomes over a 3-year period in patients with nonthymomatous myasthenia gravis, with fewer treatment-associated symptoms related to immunosuppressive medications and lower distress levels related to symptoms.
Randomized Trial of Thymectomy in Myasthenia Gravis.
TLDR
Patients 18 to 65 years of age who had generalized nonthymomatous myasthenia gravis with a disease duration of less than 5 years were included if they had Myastshenia Gravis Foundation of America clinical class II to IV disease and elevated circulating concentrations of acetylcholine-receptor antibody.
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