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- Publications
- Influence
An emergent poxvirus from humans and cattle in Rio de Janeiro State: Cantagalo virus may derive from Brazilian smallpox vaccine.
- C. R. Damaso, J. Esposito, R. Condit, N. Moussatché
- Biology, Medicine
- Virology
- 25 November 2000
The biological properties of poxvirus isolates from skin lesions on dairy cows and milkers during recent exanthem episodes in Cantagalo County, Rio de Janeiro State, Brazil, were more like vaccinia… Expand
In a nutshell: structure and assembly of the vaccinia virion.
- R. Condit, N. Moussatché, P. Traktman
- Biology, Medicine
- Advances in virus research
- 2006
Poxviruses comprise a large family of viruses characterized by a large, linear dsDNA genome, a cytoplasmic site of replication and a complex virion morphology. The most notorious member of the… Expand
Blockade of Interferon Induction and Action by the E3L Double-Stranded RNA Binding Proteins of Vaccinia Virus
- Y. Xiang, R. Condit, S. Vijaysri, B. Jacobs, B. Williams, R. Silverman
- Biology, Medicine
- Journal of Virology
- 15 May 2002
ABSTRACT The vaccinia virus E3L gene encodes two double-stranded RNA binding proteins that promote viral growth and pathogenesis through suppression of innate immunity. To explore how E3L enables… Expand
Isolation, characterization, and physical mapping of temperature-sensitive mutants of vaccinia virus.
- R. Condit, A. Motyczka, G. Spizz
- Biology, Medicine
- Virology
- 30 July 1983
Thirty-nine new temperature-sensitive mutants of vaccinia virus have been isolated, expanding a previously reported collection of mutants (R. C. Condit and A. Motyczka, Virology 113, 224-241, 1981)… Expand
Isolation and preliminary characterization of temperature-sensitive mutants of vaccinia virus.
- R. Condit, A. Motyczka
- Biology, Medicine
- Virology
- 1 August 1981
Abstract Methods have been developed for rapid isolation and genetic analysis of vaccinia virus mutants. These methods include: (1) monitoring mutagenesis by measuring conversion of wild-type,… Expand
Characterization of the interactions among vaccinia virus transcription factors G2R, A18R, and H5R.
- E. P. Black, N. Moussatché, R. Condit
- Biology, Medicine
- Virology
- 5 June 1998
Prior genetic analysis suggests that there may exist an interaction between the products of the vaccinia virus genes A18R, a putative negative transcription elongation factor, and G2R, a putative… Expand
Nucleotide sequence and genetic map of the 16-kb vaccinia virus HindIII D fragment.
- E. G. Niles, R. Condit, P. Caro, K. Davidson, L. Matusick, J. Seto
- Biology, Medicine
- Virology
- 1 August 1986
We have determined the nucleotide sequence of the 16,059-bp HindIII D fragment from vaccinia virus strain WR. Translation in all 6 reading frames reveals a set of 22 open reading frames (ORFs), which… Expand
Temperature-sensitive mutants in the vaccinia virus A18R gene increase double-stranded RNA synthesis as a result of aberrant viral transcription.
- C. Bayliss, R. Condit
- Biology, Medicine
- Virology
- 1 May 1993
Mutations in the vaccinia gene A18R cause activation of the cellular ribonucleolytic 2-5A pathway. To determine the mechanism of 2-5A pathway activation, mutant infections were analyzed for synthesis… Expand
Innate Immune Response of Human Plasmacytoid Dendritic Cells to Poxvirus Infection Is Subverted by Vaccinia E3 via Its Z-DNA/RNA Binding Domain
Plasmacytoid dendritic cells (pDCs) play important roles in antiviral innate immunity by producing type I interferon (IFN). In this study, we assess the immune responses of primary human pDCs to two… Expand
The Vaccinia Virus A18R DNA Helicase Is a Postreplicative Negative Transcription Elongation Factor
- Y. Xiang, D. Simpson, J. Spiegel, A. Zhou, R. Silverman, R. Condit
- Biology, Medicine
- Journal of Virology
- 1 September 1998
ABSTRACT Loss of vaccinia virus A18R gene function results in an aberrant transcription profile termed promiscuous transcription, defined as transcription within regions of the genome which are… Expand