R. Coleman

Publications146
h-index43
Citations7,299
Highly Influential Citations337
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International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.
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GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues.
Quantitative gene expression data are often normalized to the expression levels of control or so-called "housekeeping" genes. An inherent assumption in the use of housekeeping genes is that… Expand
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A novel inhibitory prostanoid receptor in piglet saphenous vein.
A range of prostanoid agonists were tested for activity on isolated ring preparations of piglet saphenous vein. The selective TxA2-mimetic (TP-receptor agonist), U-46619, contracted the preparation… Expand
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COMPARISON OF THE ACTIONS OF U‐46619, A PROSTAGLANDIN H2‐ANALOGUE, WITH THOSE OF PROSTAGLANDIN H2 AND THROMBOXANE A2 ON SOME ISOLATED SMOOTH MUSCLE PREPARATIONS
1 The actions of the prostaglandin H2 (PGH2) analogue, U‐46619, have been compared with those of PGH2 and thromboxane A2 (TxA2) on a range of isolated smooth muscle preparations in a superfusion… Expand
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EP4 prostanoid receptor‐mediated vasodilatation of human middle cerebral arteries
Dilatation of the cerebral vasculature is recognised to be involved in the pathophysiology of migraine. Furthermore, elevated levels of prostaglandin E2 (PGE2) occur in the blood, plasma and saliva… Expand
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GR159897, a potent non-peptide antagonist at tachykinin NK2 receptors.
GR159897 ((R)-1-[2-(5-fluoro-1H-indol-3-yl)ethyl]-4-methoxy-4- [(phenylsulfinyl)methyl]piperidine) is a novel, highly potent and selective non-peptide antagonist at tachykinin NK2 receptors. GR159897… Expand
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Salmeterol, a novel, long‐acting β2‐adrenoceptor agonist: characterization of pharmacological activity in vitro and in vivo
1 Salmeterol, a novel, long‐acting β‐adrenoceptor agonist, has been compared with isoprenaline and salbutamol for activity in vitro on a range of β‐adrenoceptor containing preparations from… Expand
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New evidence with selective agonists and antagonists for the subclassification of PGE2-sensitive (EP) receptors.
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Characterization of dilator prostanoid receptors in the fetal rabbit ductus arteriosus.
The purpose of this study was to determine which receptors mediate the dilator effects of prostaglandins (PGs) on the ductus arteriosus of the fetal rabbit. Isolated rings of the vessel from fetal… Expand
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Characterization of the PGE receptor subtype mediating inhibition of superoxide production in human neutrophils
1 The aims of this study were to characterize the EP receptor subtype mediating the inhibition of superoxide anion generation by formyl methionyl leucine phenylalanine (FMLP)‐stimulated human… Expand
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