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A pilot study quantifying the shape of tidal breathing waveforms using centroids in health and COPD
During resting tidal breathing the shape of the expiratory airflow waveform differs with age and respiratory disease. While most studies quantifying these changes report time or volume specificExpand
[Angiotensin II stimulates endothelin-1 release from human endothelial cells].
Endothelin-1 (ET-1) is an endothelium-derived vasoconstrictor peptide isolated from the culture supernatant of porcine aortic endothelial cells. This 21 amino-acid residue peptide has potentExpand
Analysis of tidal breathing profiles in cystic fibrosis and COPD.
STUDY OBJECTIVES To explore the flow and time domain characteristics of resting tidal airflow profiles in the presence of obstructive airway disease. METHODS Spirometry was performed on 81 adultsExpand
Classification of Tidal Breathing Airflow Profiles Using Statistical Hierarchal Cluster Analysis in Idiopathic Pulmonary Fibrosis
In idiopathic pulmonary fibrosis (IPF) breathing pattern changes with disease progress. This study aims to determine if unsupervised hierarchal cluster analysis (HCA) can be used to define airflowExpand
Breathing pattern and breathlessness in idiopathic pulmonary fibrosis: An observational study
Idiopathic pulmonary fibrosis (IPF) is characterized by progressive decline in lung function and increasing dyspnoea. The aim of this study was to investigate the relationship among IPF, pulmonaryExpand
[The proteolytic etiopathogenesis of pulmonary emphysema].
Laennec and later workers attributed the aetiopathogenesis of emphysema to mechanical causes. This view has been superseded by the current proteolytic theory. It is now believed that the destructionExpand