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Bezlotoxumab: Could This be the Answer for Clostridium difficile Recurrence?
Objective: To review the pharmacology, pharmacokinetics, efficacy, safety, and place in therapy of bezlotoxumab (BEZ), a novel monoclonal antibody against Clostridium difficile toxin B. Data Sources:Expand
Restriction-free antimicrobial stewardship initiative targeting fluoroquinolone reduction across a regional health-system
Summary Background Fluoroquinolone (FQ) antibiotics have become a target of many antimicrobial stewardship programmes. Multiple post-marketing warnings from the Food and Drug Administration cautionExpand
Assessment of a Healthcare-Associated Pneumonia (HCAP) Risk Stratification and Empiric Treatment Guideline: A New Antimicrobial Stewardship Initiative
Abstract Background Risk stratification of HCAP patients is a possible Antimicrobial Stewardship (AST) intervention for the treatment of multidrug resistant (MDR) Gram-negative (GN) vs.Expand
1092. Impact of Relieving Infectious Diseases Fellows from Off-Hour/Weekend Antimicrobial Stewardship Coverage
Abstract Background Antimicrobial stewardship programs (ASPs) often utilize Infectious Diseases fellows (IDFs) to cover pre-authorization processes during evening and weekend hours. IDFs oftenExpand
54. Microbiologic Characterization and Antibacterial Use in Hospitalized Adults with covid-19 Infection
Background: Coronavirus disease 2019 (CoVID-19) admissions, oft complicated by an uncertain trajectory, lent to treatment influenced by supposition Respiratory bacterial co-infection frequently wasExpand
Grading the Impact of a Standardized Β Lactam Antibiotic Allergy Assessment Protocol for Treatment Decisions: An Antimicrobial Stewardship Target
Abstract Background Approximately 30% of patients at our institution have β-lactam (BL) antibiotic allergies documented in their medical record. This translates to high use of non-β-lactams (NBL) orExpand
215. Unintended Consequences of Fluoroquinolone Stewardship: Impact on Overall Antimicrobial Use Data and Implications for Benchmarking
Abstract Background Antimicrobial stewardship (AS) initiative to reduce fluoroquinolone (FQ) use in targeted diagnosis-related groups (DRG) across 14 acute care hospitals was launched in 2016 due toExpand