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Identification of a subpopulation of macrophages in mammary tumor-bearing mice that are neither M1 nor M2 and are less differentiated.
Systemic and local immune deficiency is associated with cancer, and the role of M2 tumor-associated macrophages in this phenomenon is well recognized. However, the immune status of macrophages from… Expand
Alterations in macrophages and monocytes from tumor-bearing mice: evidence of local and systemic immune impairment
Macrophages are cells of the innate immune system involved in critical activities such as maintaining tissue homeostasis and immune surveillance. Pro-inflammatory macrophages M1 are responsible for… Expand
Intraoperative Parathyroid Hormone Monitoring: Optimal Utilization.
Intraoperative parathyroid hormone (IOPTH) monitoring is a highly accurate surgical adjunct used to determine the extent of surgery in the setting of primary hyperparathyroidism. It is the successful… Expand
Specialized dendritic cells induce tumor-promoting IL-10+IL-17+ FoxP3neg regulatory CD4+ T cells in pancreatic carcinoma
The drivers and the specification of CD4+ T cell differentiation in the tumor microenvironment and their contributions to tumor immunity or tolerance are incompletely understood. Using models of… Expand
Tumor microenvironment profoundly modifies functional status of macrophages: peritoneal and tumor-associated macrophages are two very different subpopulations.
- Dayron Rodríguez, Risset Silvera, +5 authors M. Torroella-Kouri
- Biology, Medicine
- Cellular immunology
- 1 May 2013
Macrophages are key players in the inflammatory response. In this study, we tested the hypothesis that although all macrophage subpopulations in tumor hosts are affected by the disease, it is the… Expand
Blood monocytes from mammary tumor-bearing mice: early targets of tumor-induced immune suppression?
- R. Caso, Risset Silvera, R. Carrio, Viyaya Iragavarapu-Charyulu, R. Gonzalez-Perez, M. Torroella-Kouri
- Biology, Medicine
- International journal of oncology
- 1 October 2010
We have previously shown that peritoneal macrophages from mice bearing advanced D1-DMBA3 mammary tumors are impaired in their inflammatory functions but are not alternatively activated either and are… Expand
Outcomes of minimally invasive sleeve resection.
Background Sleeve resection allows for preservation of lung parenchyma and improved long-term outcomes when compared with pneumonectomy. Little is known about minimally invasive sleeve resection,… Expand
Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma
Purpose: The majority of broad-panel tumor genomic profiling has used a gene-centric approach, although much of that data is unused in clinical decision making. We hypothesized that a pathway-centric… Expand
Assessment of Quality Outcomes and Learning Curve for Robot-Assisted Minimally Invasive McKeown Esophagectomy
This study aimed to identify the results of the quality assessment and the learning curve of robot-assisted minimally invasive McKeown esophagectomy (RAMIE-MK). The study retrospectively reviewed the… Expand
Liposomal bupivacaine in minimally invasive thoracic surgery: something is rotten in the state of Denmark.
In the last decade, incorporation of minimally invasive approaches for a vast array of thoracic procedures has improved perioperative patient outcomes, however adequate postoperative pain control for… Expand