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Serotonin and brain function: a tale of two receptors
Previous attempts to identify a unified theory of brain serotonin function have largely failed to achieve consensus. In this present synthesis, we integrate previous perspectives with new and olderExpand
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Psilocybin with psychological support for treatment-resistant depression: six-month follow-up
RationaleRecent clinical trials are reporting marked improvements in mental health outcomes with psychedelic drug-assisted psychotherapy.ObjectivesHere, we report on safety and efficacy outcomes forExpand
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Psychedelics and connectedness
Psychedelic drugs are creating ripples in psychiatry as evidence accumulates of their therapeutic potential. An important question remains unresolved however: how are psychedelics effective? WeExpand
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Effects of psilocybin therapy on personality structure
To explore whether psilocybin with psychological support modulates personality parameters in patients suffering from treatment‐resistant depression (TRD).
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User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study
This study used a web-based questionnaire to investigate user perceptions of the benefits and harms of hallucinogenic drug use. Over 600 forms were submitted. Users were asked to comment on the acuteExpand
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LSD enhances suggestibility in healthy volunteers
RationaleLysergic acid diethylamide (LSD) has a history of use as a psychotherapeutic aid in the treatment of mood disorders and addiction, and it was also explored as an enhancer of mindExpand
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Current and former ecstasy users report different sleep to matched controls: a web-based questionnaire study
Abstract This study sought to test the association between ecstasy-use and abnormal sleep. An anonymous web-based questionnaire containing questions on drug use and sleep was completed by 1035Expand
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Psychiatry’s next top model: cause for a re-think on drug models of psychosis and other psychiatric disorders
Despite the widespread application of drug modelling in psychiatric research, the relative value of different models has never been formally compared in the same analysis. Here we compared theExpand
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LSD enhances the emotional response to music
RationaleThere is renewed interest in the therapeutic potential of psychedelic drugs such as lysergic acid diethylamide (LSD). LSD was used extensively in the 1950s and 1960s as an adjunct inExpand
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Psilocybin with psychological support improves emotional face recognition in treatment-resistant depression
RationaleDepressed patients robustly exhibit affective biases in emotional processing which are altered by SSRIs and predict clinical outcome.ObjectivesThe objective of this study is to investigateExpand
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