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Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM.
These features within the genome sequence of L. acidophilus are likely to contribute to the organisms' gastric survival and promote interactions with the intestinal mucosa and microbiota. Expand
Functional and comparative genomic analyses of an operon involved in fructooligosaccharide utilization by Lactobacillus acidophilus
This is a description of a previously undescribed gene locus involved in transport and catabolism of FOS compounds, which can promote competition of beneficial microorganisms in the human gastrointestinal tract. Expand
Genetic Analysis of Two Bile Salt Hydrolase Activities in Lactobacillus acidophilus NCFM
Targeted inactivation of these genes via chromosomal insertion of an integration vector demonstrated different substrate specificities for these two enzymes. Expand
Revival and identification of bacterial spores in 25- to 40-million-year-old Dominican amber.
A bacterial spore was revived, cultured, and identified from the abdominal contents of extinct bees preserved for 25 to 40 million years in buried Dominican amber that indicated that the ancient bacterium is most closely related to extant Bacillus sphaericus. Expand
Species-specific identification of commercial probiotic strains.
Products containing probiotic bacteria are gaining popularity, increasing the importance of their accurate speciation. Unfortunately, studies have suggested that improper labeling of probioticExpand
Discovering lactic acid bacteria by genomics
This review summarizes a collection of lactic acid bacteria that are now undergoing genomic sequencing and analysis, with each overview discussing the organisms fundamental and practical significance, nvironmental habitat, and its role in fermentation, bioprocessing, or probiotics. Expand
Identification and Inactivation of Genetic Loci Involved with Lactobacillus acidophilus Acid Tolerance
Interestingly, each integrant also exhibited an adaptive acid response during logarithmic growth, indicating that multiple mechanisms are present and orchestrated in L. acidophilus in response to acid challenge. Expand
Complete Genomic Sequence of Bacteriophage B3, a Mu-Like Phage of Pseudomonas aeruginosa
Comparison of the B3 genomic organization with that of Mu revealed evidence of multiple genetic rearrangements, the most notable being the inversion of the proposed B3 immunity/early gene region, the loss of Mu-like tail genes, and an extreme leftward shift of theB3 DNA modification gene cluster. Expand
Staphylococcus succinus sp. nov., isolated from Dominican amber.
The results indicate that AMg-D1T and AMG-D2 represent a novel species, which was named Staphylococcus succinus sp. Expand
Micrococcus luteus - Survival in Amber
Evidence is demonstrated supporting the view that non-spore-forming cocci from a 120-million-year-old block of amber have numerous adaptations for survival in extreme, nutrient-poor environments, traits that will assist in this bacteria’s persistence and dispersal in the environment. Expand