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Saccharopolyspora spinosa sp. nov. isolated from soil collected in a sugar mill rum still
A new Saccharopolyspora species isolated from soil collected in a sugar mill rum still is described. This organism is characterized by pale yellowish pink aerial hyphae that bear long chains of…
Discovery, Isolation, and Structure Elucidation of a Family of Structurally Unique, Fermentation-Derived Tetracyclic Macrolides
A83543A-D, unique fermentation-derived tetracyclic macrolides
A80915, a new antibiotic complex produced by Streptomyces aculeolatus. Discovery, taxonomy, fermentation, isolation, characterization, and antibacterial evaluation.
Mechanism of action studies demonstrated nearly complete inhibition of macromolecular biosynthesis by A80915 factors A through D, which show antimicrobial activity against Gram-positive aerobic and anaerobic organisms in vitro.
Biosynthesis of aflatoxin. Conversion of norsolorinic acid and other hypothetical intermediates into aflatoxin B1.
Step of dichlorvos inhibition in the pathway of aflatoxin biosynthesis.
Dichlorvos appears to block an enzymatic step in the aflatoxin biosynthetic pathway, which lies beyond averufin but before sterigmatocystin, at the formation of the orange pigment.
A83586C, a new depsipeptide antibiotic.
A culture identified as Streptomyces karnatakensis was found to produce a novel cyclic hexadepsipeptide antibiotic designated A83586C, which had potent Gram-positive activity in vitro but lacked in vivo efficacy in mice.
Method for the detection and quantitation of chitinase inhibitors in fermentation broths; isolation and insect life cycle effect of A82516.
- P. Somers, R. C. Yao, L. E. Doolin, M. McGowan, D. Fukuda, J. S. Mynderse
- BiologyThe Journal of antibiotics
- 25 December 1987
Allosamidin, a recently reported chitinase inhibitor in vitro, has spectral properties identical to A82516, and was found to have an IC50 of 3.7 X 10(-6) M for S. griseus chit inase.
Amycolatopsis alba sp. nov., isolated from soil.
A new Amycolatopsis species isolated from soil produces a new glycopeptide antibiotic related to vancomycin and is characterized by white aerial hyphae that bear long chains of cylindrical conidia.
Streptosporangium carneum sp. nov. isolated from soil
This isolate has chemical and morphological properties that are consistent with the properties of the genus Streptosporangium, and a comparison with previously described species indicated that this organism differs from previous described species.