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- Publications
- Influence
Synaptic vesicle tethering and the CaV2.2 distal C-terminal
- F. Wong, Arup R. Nath, R. C. Chen, Sabiha R. Gardezi, Q. Li, E. F. Stanley
- Biology, Medicine
- Front. Cell. Neurosci.
- 7 March 2014
Evidence that synaptic vesicles (SVs) can be gated by a single voltage sensitive calcium channel (CaV2.2) predict a molecular linking mechanism or “tether” (Stanley, 1993). Recent studies have… Expand
α-Synuclein Membrane Association Is Regulated by the Rab3a Recycling Machinery and Presynaptic Activity*♦
- R. C. Chen, S. Wislet-Gendebien, +6 authors A. Tandon
- Biology, Medicine
- The Journal of Biological Chemistry
- 23 January 2013
Background: α-Synuclein is known to undergo exchange between membrane and cytosolic compartments. Results: α-Synuclein interacts with GTP-bound Rab3a on synaptic vesicles, and its dissociation is… Expand
The Calcium Channel C-Terminal and Synaptic Vesicle Tethering: Analysis by Immuno-Nanogold Localization
- R. C. Chen, Q. Li, Christine A. Snidal, Sabiha R. Gardezi, E. F. Stanley
- Biology, Medicine
- Front. Cell. Neurosci.
- 30 March 2017
At chemical synapses the incoming action potential triggers the influx of Ca2+ through voltage-sensitive calcium channels (CaVs, typically CaV2.1 and 2.2) and the ions binds to sensors associated… Expand
Cryoloading: introducing large molecules into live synaptosomes
- Arup R. Nath, R. C. Chen, E. F. Stanley
- Medicine, Biology
- Front. Cell. Neurosci.
- 23 January 2014
Neurons communicate with their target cells primarily by the release of chemical transmitters from presynaptic nerve terminals. The study of CNS presynaptic nerve terminals, isolated as synaptosomes… Expand
Molecular Characterization of an SV Capture Site in the Mid-Region of the Presynaptic CaV2.1 Calcium Channel C-Terminal
- Christine A. Snidal, Q. Li, +4 authors E. F. Stanley
- Chemistry, Medicine
- Front. Cell. Neurosci.
- 11 May 2018
Neurotransmitter is released from presynaptic nerve terminals at fast-transmitting synapses by the action potential-gating of voltage dependent calcium channels (CaV), primarily of the CaV2.1 and… Expand
A MPCDM-enabled Product Concept Design via User Involvement Approach
- C. Wang, R. C. Chen
- Computer Science, Engineering
- Concurr. Eng. Res. Appl.
- 1 March 2011
TLDR
Diabetic Footwear: Materials Choices and Design
- J. Tagang, R. C. Chen, E. Pei
- Medicine
- 9 June 2016
The incidence and prevalence rates of diabetes worldwide are increasing and foot complications are rising parallel. There is however lack of adequate knowledge about the role of appropriate footwear… Expand
Determination of Comfort and Performance Properties of Upper Materials for Diabetic Footwear Construction
- R. C. Chen, E. Pei, N. Higgett, J. Tagang
- Engineering
- 23 August 2014
This work investigates comfort and performance properties of selected shoe upper materials manufactured in Nigeria for their suitability for diabetic footwear construction. The research was carried… Expand
Sustainable Innovation: Footwear Material Choices and Design for People Suffering with Diabetes
- I. J. Tagang, R. C. Chen, E. Pei, N. Higgett
- Engineering
- 2013
8 Regulation of-Synuclein Membrane Binding and Its Implications
1.1 Parkinson’s disease and Lewy bodies Parkinson’s disease (PD) is the most prevalent neurodegenerative disease that affects motor control, although dementia, depression, and other psychiatric… Expand