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Evidence for Placental Abnormality as the Major Cause of Mortality in First-Trimester Somatic Cell Cloned Bovine Fetuses1
- J. Hill, R. Burghardt, +7 authors M. Westhusin
- Medicine, Biology
- Biology of reproduction
- 1 December 2000
Abstract The production of cloned animals is, at present, an inefficient process. This study focused on the fetal losses that occur between Days 30–90 of gestation. Fetal and placental… Expand
Implantation mechanisms: insights from the sheep.
Implantation in all mammals involves shedding of the zona pellucida, followed by orientation, apposition, attachment and adhesion of the blastocyst to the endometrium. Endometrial invasion does not… Expand
HOTAIR IS A NEGATIVE PROGNOSTIC FACTOR AND EXHIBITS PRO-ONCOGENIC ACTIVITY IN PANCREATIC CANCER
HOTAIR is a long intervening non-coding RNA (lincRNA) that associates with the Polycomb Repressive Complex 2 (PRC2) and overexpression is correlated with poor survival for breast, colon and liver… Expand
Comparative aspects of implantation.
Uterine receptivity to implantation of blastocysts in mammals includes hatching from zona pellucida, precontact with uterine luminal (LE) and superficial glandular (sGE) epithelia and orientation of… Expand
Triennial Growth Symposium: important roles for L-glutamine in swine nutrition and production.
L-Glutamine (Gln) has traditionally not been considered a nutrient needed in diets for livestock species or even mentioned in classic animal nutrition textbooks. This is due to previous technical… Expand
Spatial and temporal analyses of integrin and Muc-1 expression in porcine uterine epithelium and trophectoderm in vivo.
The spatial and temporal expressions of Muc-1, selected integrin subunits, and extracellular matrix components in porcine uterine epithelium from estrous (Days 0, 4, 8, 10-15) and early pregnant… Expand
Progesterone and Placental Hormone Actions on the Uterus: Insights from Domestic Animals1
Abstract Progesterone is unequivocally required for maternal support of conceptus (embryo/fetus and associated extraembryonic membranes) survival and development. In cyclic sheep, progesterone is… Expand
Pregnancy recognition and conceptus implantation in domestic ruminants: roles of progesterone, interferons and endogenous retroviruses.
- T. Spencer, G. Johnson, F. Bazer, R. Burghardt, M. Palmarini
- Biology, Medicine
- Reproduction, fertility, and development
The present review highlights new information on pregnancy recognition and conceptus development and implantation in sheep with respect to regulation by progesterone, interferons and endogenous… Expand
Novel pathways for implantation and establishment and maintenance of pregnancy in mammals.
- F. Bazer, G. Wu, T. Spencer, G. Johnson, R. Burghardt, K. Bayless
- Biology, Medicine
- Molecular human reproduction
- 1 March 2010
Uterine receptivity to implantation varies among species, and involves changes in expression of genes that are coordinate with attachment of trophectoderm to uterine lumenal and superficial glandular… Expand
Impacts of amino acid nutrition on pregnancy outcome in pigs: mechanisms and implications for swine production.
Pigs suffer up to 50% embryonic and fetal loss during gestation and exhibit the most severe naturally occurring intrauterine growth retardation among livestock species. Placental insufficiency is a… Expand