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The Brain's Default Network
TLDR
Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease. Expand
An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest
TLDR
An automated labeling system for subdividing the human cerebral cortex into standard gyral-based neuroanatomical regions is both anatomically valid and reliable and may be useful for both morphometric and functional studies of the cerebral cortex. Expand
The organization of the human cerebral cortex estimated by intrinsic functional connectivity.
TLDR
The organization of these large-scale cerebral networks in the human cerebrum was explored using resting-state functional connectivity MRI and their potential evolutionary expansion in humans to support cognition was discussed. Expand
Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease
TLDR
To identify regions of high connectivity in the human cerebral cortex, a computationally efficient approach was applied to map the degree of intrinsic functional connectivity across the brain and explored whether the topography of hubs could explain the pattern of vulnerability in Alzheimer's disease (AD). Expand
Intrinsic functional connectivity as a tool for human connectomics: theory, properties, and optimization.
TLDR
The brevity and robustness of fcMRI positions it as a powerful tool for large-scale explorations of genetic influences on brain architecture and how it can be combined with HARDI techniques to support the emerging field of human connectomics. Expand
The influence of head motion on intrinsic functional connectivity MRI
TLDR
Head motion was associated with decreased functional coupling in the default and frontoparietal control networks--two networks characterized by coupling among distributed regions of association cortex and other network measures increased with motion including estimates of local functional coupling and coupling between left and right motor regions. Expand
Open Access Series of Imaging Studies (OASIS): Cross-sectional MRI Data in Young, Middle Aged, Nondemented, and Demented Older Adults
TLDR
Automated calculation of whole-brain volume and estimated total intracranial volume are presented to demonstrate use of the data for measuring differences associated with normal aging and Alzheimer's disease. Expand
Biological Insights From 108 Schizophrenia-Associated Genetic Loci
TLDR
Associations at DRD2 and several genes involved in glutamatergic neurotransmission highlight molecules of known and potential therapeutic relevance to schizophrenia, and are consistent with leading pathophysiological hypotheses. Expand
Self-projection and the brain
TLDR
It is speculated that envisioning the future (prospection), remembering the past, conceiving the viewpoint of others (theory of mind), and possibly some forms of navigation reflect the workings of the same core brain network. Expand
Toward discovery science of human brain function
TLDR
A universal architecture of positive and negative functional connections, as well as consistent loci of inter-individual variability are demonstrated, which demonstrate that independent R-fMRI datasets can be aggregated and shared. Expand
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