Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion.
- N. Frangogiannis, M. Lindsey, M. Entman
- Biology, MedicineCirculation
- 18 August 1998
It is suggested that mast cell-derived TNF-alpha may be a crucial factor in upregulating IL-6 in infiltrating leukocytes and initiating the cytokine cascade responsible for myocyte ICAM-1 induction and subsequent neutrophil-induced injury.
Principles of drug therapy for the elderly patient.
- R. Bressler, J. Bahl
- MedicineMayo Clinic proceedings
- 1 December 2003
The underlying reasons why the elderly population is at risk of adverse drug reactions are reviewed and the principles of drug-drug interaction, metabolism, and distribution are summarized to help elderly patients receive proper pharmacological treatment.
Effect of taurine on a muscle intracellular membrane.
- R. Huxtable, R. Bressler
- Biology, ChemistryBiochimica et Biophysica Acta
- 16 November 1973
Prevention of Diabetic Nephropathy by Diet Control in the db/db Mouse
- S. Lee, R. Bressler
- MedicineDiabetes
- 1 February 1981
Results indicate that diabetic control achieved by prevention of obesity in the db/db mouse prevents the development of diabetic nephropathy.
Acetyl-CoA Carboxylase 2−/− Mutant Mice are Protected against Fatty Liver under High-fat, High-carbohydrate Dietary and de Novo Lipogenic Conditions*
- L. Abu-Elheiga, Hongmei Wu, Ziwei Gu, R. Bressler, S. Wakil
- Biology, MedicineJournal of Biological Chemistry
- 23 February 2012
De deleting ACC2 ameliorates the metabolic syndrome and protects against fatty liver despite increased de novo lipogenesis and dietary conditions known to induce obesity and diabetes.
In vitro and in vivo suppression of gluconeogenesis by inhibition of pyruvate carboxylase.
- J. Bahl, M. Matsuda, R. DeFronzo, R. Bressler
- Biology, Computer ScienceBiochemical Pharmacology
- 10 January 1997
Pharmacological regulation of blood glucose levels in non-insulin-dependent diabetes mellitus.
- R. Bressler, D. Johnson
- Medicine, BiologyArchives of Internal Medicine
- 28 April 1997
These pharmacological agents, either alone or in combination, can improve blood glucose regulation in patients with non-insulin-dependent diabetes mellitus.
Clinical Pharmacology of Oral Antidiabetic Agents
- S. Shen, R. Bressler
- Medicine
- 3 March 1977
The oral hypoglycemic agents available in the United States (Fig. 1) include the sulfonylureas tolbutamide (Orinase), chlorpropamide (Diabinese), acetohexamide (Dymelor), tolazamide (Tolinase) and ...
BIOCHEMICAL LESION OF DIPHTHERIA TOXIN IN THE HEART.
- B. Wittels, R. Bressler
- MedicineJournal of Clinical Investigation
- 1 April 1964
The pharmacology of carnitine.
- J. Bahl, R. Bressler
- ChemistryAnnual Review of Pharmacology and Toxicology
- 1987
The administration of cami tine as a pharmacological agent in various situations is viewed as derivative of its role in intermediary metabolism, generally related to fatty acid metabolism.
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