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Subtypes of thymic epithelial cells defined by neuroendocrine markers
It was shown that cells displaying immunostaining typical for individual markers reside in distinct regions of the thymus and represent subtypes within various populations of thymic epithelial cells.
Effects of galanin on proliferation and apoptosis of immature rat thymocytes.
- M. Trejter, R. Brelińska, L. Malendowicz
- BiologyInternational journal of molecular medicine
- 1 August 2002
It is indicated that galanin, probably acting through GalR1 and GalR3, exerts antiproliferative and proapoptotic effects on immature rat thymocytes, which makes it likely that this peptide plays a role in the autocrine/paracrine functional regulation of immune system in the rat.
Thymic nurse cells: Their functional ultrastructure
Characteristics of epithelial cells capable of forming complexes with thymocytes are presented, in light of the literature data and the experience of the authors, to clarify the matter.
Thymic nurse cells: division of thymocytes within complexes
- R. Brelińska
- BiologyCell and Tissue Research
- 1 December 1989
The data support the view that microenvironmental factors within TNC-c are responsible for both inducing thymocytes to enter the cell cycle and the negative selection (cell death) of someThymocytes.
Endothelin-1, acting via the A receptor subtype, stimulates thymocyte proliferation in the rat.
Characteristics of age-related changes in rat thymus: morphometric analysis and epithelial cell network in various thymic compartments
In the entire period of life the most dynamic changes were found in the cortex while the medulla was demonstrated to be a rather “stable” region, and hypertrophy and hyperplasia of superficial epithelial cells seems to functionally replace medullary cells.
Subpopulations of blood lymphocytes in patients with rheumatoid arthritis.
Thymic epithelial cells in age‐dependent involution
- R. Brelińska
- BiologyMicroscopy research and technique (Print)
- 15 December 2003
Structural and phenotypic modifications of TEC are locally controlled by complex sets of different factors and seem to represent a morphological adaptation of the gland to the process of aging.
Evidence for Less Irritation to the Peritoneal Membrane in Rats Dialyzed with Solutions Low in Glucose Degradation Products
- K. Wieczorowska-Tobis, R. Brelińska, A. Bręborowicz
- Medicine, BiologyPeritoneal dialysis international : journal of…
- 1 January 2004
A new generation of PDF with physiologic pH and low GDP level produce less irritation to the peritoneal membrane and better preserve its structural integrity, related predominantly to minimized GDP concentrations.
Studies on the involvement of endogenous neuropeptides in the control of thymocyte proliferation in the rat.
- M. Trejter, J. Warchoł, R. De Caro, R. Brelińska, G. Nussdorfer, L. Malendowicz
- BiologyHistology and histopathology
It is concluded that endogenous VIP exerts a maximal tonic inhibitory influence on the basal proliferative activity of rat thymocytes, while endogenous CCK and NT do not play a relevant modulatory role in this process.