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Toward a complete dataset of drug-drug interaction information from publicly available sources
TLDR
A comprehensive dataset of all publically available sources of PDDI information that could be identified using a comprehensive and broad search were combined into a single dataset. Expand
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Emerging practices for mapping and linking life sciences data using RDF - A case series
TLDR
This paper presents the workflow along with four case studies that demonstrate the workflow and addresses many of the challenges that may be faced when creating new Linked Data resources. Expand
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Overview of the TAC 2018 Drug-Drug Interaction Extraction from Drug Labels Track
TLDR
This paper describes the Drug-Drug Interaction Extraction Extraction from Drug Labels Track, part of the 2018 Text Analysis Conference (TAC). Expand
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Accuracy of an automated knowledge base for identifying drug adverse reactions
TLDR
We explore a method for automatically aggregating disparate sources of information together into a single repository, developing a predictive model to classify drug-adverse event relationships, and applying those predictions to a real world problem of identifying negative controls for statistical method calibration. Expand
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A review of the effectiveness of antidepressant medications for depressed nursing home residents.
BACKGROUND Antidepressant medications are the most common psychopharmacologic therapy used to treat depressed nursing home (NH) residents. Despite a significant increase in the rate of antidepressantExpand
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Bridging Islands of Information to Establish an Integrated Knowledge Base of Drugs and Health Outcomes of Interest
The entire drug safety enterprise has a need to search, retrieve, evaluate, and synthesize scientific evidence more efficiently. This discovery and synthesis process would be greatly acceleratedExpand
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Bringing clinical pharmacogenomics information to pharmacists: A qualitative study of information needs and resource requirements
TLDR
We conducted qualitative inquiries with 14 pharmacists representing 6 clinical environments, and used the results of those inquiries to develop a model of pharmacists' pharmacogenomics resource requirements. Expand
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Computing with evidence: Part I: A drug-mechanism evidence taxonomy oriented toward confidence assignment
TLDR
We present a new evidence taxonomy that, when combined with a set of inclusion criteria, enable drug experts to specify what their confidence in a drug mechanism assertion would be if it were supported by a specific set of evidence. Expand
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Dynamic enhancement of drug product labels to support drug safety, efficacy, and effectiveness
Out-of-date or incomplete drug product labeling information may increase the risk of otherwise preventable adverse drug events. In recognition of these concerns, the United States Federal DrugExpand
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Using natural language processing to identify pharmacokinetic drug-drug interactions described in drug package inserts
The package insert (aka drug product label) is the only publicly-available source of information on drug-drug interactions (DDIs) for some drugs, especially newer ones. Thus, an automated method forExpand
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