• Publications
  • Influence
THE HOST RESPONSE TO CALMETTE-GUÉRIN BACILLUS INFECTION IN MICE
Heterologous organisms (L. monocytogenes and S. typhimurium) were used to study the rate of development, magnitude, and persistence of the antimicrobial resistance engendered in mice by vaccinationExpand
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T Cell Response to Viral and Bacterial Infection
  • R. Blanden
  • Biology, Medicine
  • Transplantation reviews
  • 1 June 1974
TTie adaptive immune response to antigens of infectious agents is an. important component of vertebrate defence mechanisms. In many itistances, a humoral antibody response plays a key protectiveExpand
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MECHANISMS OF ACQUIRED RESISTANCE IN MOUSE TYPHOID
Experiments in vitro comparing normal mouse peritoneal macrophages with cells from Salmonella typhimurium-infected mice have shown that the "immune" macrophages have conspicuously enhancedExpand
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Specificity of Virus‐Immune Effector T Cells for H‐2K or H‐2D Compatible Interactions: Implications for H‐Antigen Diversity
Our interest in immunogenetics started with the quite fortuitous finding that cytotoxic thymus-derived lymphocytes (T cells) from mice infected acutely with lymphocytic choriomeningitis virus (LCMV)Expand
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HOST-PARASITE RELATIONS IN MOUSE TYPHOID
The development of acquired resistance to Salmonella typhimurium has been studied in mice infected intravenously with small numbers of streptomycin-sensitive or streptomycin-resistant organisms. ByExpand
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INFECTION-IMMUNITY IN EXPERIMENTAL SALMONELLOSIS
Salmonella enteritidis is highly virulent for the mouse causing an infection resembling mouse typhoid. Survivors of the infection are completely resistant to reinfection and eliminate a largeExpand
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MECHANISMS OF RECOVERY FROM A GENERALIZED VIRAL INFECTION: MOUSEPOX
  • R. Blanden
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1 May 1971
Histological and immunofluorescence techniques showed that mononuclear cells invaded virus-infected foci in the livers of passively immunized mice within 10 hr of the receipt of immune spleen cellsExpand
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Interferon gamma is involved in the recovery of athymic nude mice from recombinant vaccinia virus/interleukin 2 infection
Athymic nude mice recover from an infection with recombinant vaccinia virus (VV) encoding murine interleukin 2 (IL-2), but treatment with a mAb to IL-2 accentuated infection. Administration of a mAbExpand
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The flavivirus nonstructural protein NS3 is a dominant source of cytotoxic T cell peptide determinants.
Vaccinia virus recombinants encoding regions of the Murray Valley encephalitis virus (MVE) genome, which together cover the entire viral coding region, were employed to identify the MVE protein whichExpand
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Elevated natural killer cell responses in mice infected with recombinant vaccinia virus encoding murine IL-2.
The role of cytotoxic T cells and NK cells in the recovery of immunodeficient, athymic, nude mice infected with a recombinant vaccinia virus (VV) encoding murine IL-2 was investigated. KineticExpand
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