R. Bissonnette

Publications295
h-index52
Citations9,412
Highly Influential Citations266
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The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic…
TLDR
In RA, tumour necrosis factor inhibitors and methotrexate are associated with a decreased risk of all CVEs while corticosteroids and NSAIDs are associatedwith an increased risk while limited evidence suggests that systemic therapies are associatedWith a decrease in all CVE risk.
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Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005.
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A Phase 2 Trial of Guselkumab versus Adalimumab for Plaque Psoriasis.
TLDR
The results of this phase 2 trial suggest that guselkumab may be an effective therapy for plaque Psoriasis and that control of psoriasis can be achieved with specific anti-interleukin-23 therapy.
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Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial
Despite unmet need, 15 years have passed since a topical therapy with a new mechanism of action for atopic dermatitis (AD) has been approved. Janus kinase (JAK) inhibitor treatment effect via topical…
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Efficacy and safety of oral alitretinoin (9‐cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double‐blind,…
Background  Patients with severe chronic hand eczema (CHE) refractory to topical corticosteroids currently have limited treatment options suited for chronic use, and few controlled clinical studies…
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Daylight photodynamic therapy for actinic keratosis: an international consensus
Photodynamic therapy (PDT) is an attractive therapy for non‐melanoma skin cancers including actinic keratoses (AKs) because it allows treatment of large areas; it has a high response rate and results…
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Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis
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Baricitinib in patients with moderate‐to‐severe atopic dermatitis and inadequate response to topical corticosteroids: results from two randomized monotherapy phase III trials
Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, effectively reduced atopic dermatitis (AD) severity in a phase II study with concomitant topical corticosteroids.
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A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis
Tofacitinib (CP‐690,550) is a novel Janus kinase inhibitor in development as an oral formulation for the treatment of several inflammatory diseases including psoriasis.
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Efficacy and Safety of Oral Janus Kinase 1 Inhibitor Abrocitinib for Patients With Atopic Dermatitis
TLDR
The findings of this study show that 12 weeks of once-daily treatment with 200 mg or 100 mg of oral abrocitinib resulted in significant improvement in the signs and symptoms of atopic dermatitis.
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