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Construction of a 3D probabilistic atlas of human cortical structures
TLDR
We describe the construction of a digital brain atlas composed of data from manually delineated MRI data. Expand
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Neuropsychology of first-episode schizophrenia: initial characterization and clinical correlates.
OBJECTIVE Neuropsychological impairments are well documented in schizophrenia and are important targets of treatment. Information about the severity and pattern of deficits after treatment for theExpand
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The Catechol-O-Methyltransferase Polymorphism: Relations to the Tonic–Phasic Dopamine Hypothesis and Neuropsychiatric Phenotypes
Diverse phenotypic associations with the catechol-O-methyltransferase (COMT) Val158Met polymorphism have been reported. We suggest that some of the complex effects of this polymorphism be understoodExpand
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Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder.
OBJECTIVE Follow-up studies have found that a substantial number of patients with schizophrenia achieve full recovery (i.e., sustained improvement in both symptoms and social/vocational functioning)Expand
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Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder.
BACKGROUND We examined relapse after response to a first episode of schizophrenia or schizoaffective disorder. METHODS Patients with first-episode schizophrenia were assessed on measures ofExpand
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Adolescent immaturity in attention-related brain engagement to emotional facial expressions
TLDR
We used functional magnetic resonance imagining (fMRI) with adolescents and adults to examine developmental differences in activation in a paradigm that involved selective attention during the viewing of emotionally engaging face stimuli. Expand
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Longitudinal study of brain morphology in first episode schizophrenia
BACKGROUND Beginning with Kraepelin, schizophrenia has been viewed as a progressive disorder. Although numerous studies of the longitudinal course of schizophrenia have demonstrated the clinicalExpand
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Orbital frontal and amygdala volume reductions in obsessive-compulsive disorder.
BACKGROUND Functional neuroimaging studies have implicated the frontal lobes and the hippocampus-amygdala complex in the pathophysiology of obsessive-compulsive disorder (OCD). These brain regionsExpand
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Relationships between IQ and regional cortical gray matter thickness in healthy adults.
Prior studies show positive correlations between full-scale intelligence quotient (FSIQ) and cerebral gray matter measures. Few imaging studies have addressed whether general intelligence is relatedExpand
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Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial.
CONTEXT Neurocognitive impairment in schizophrenia is severe and is an important predictor of functional outcome. The relative effect of the second-generation (atypical) antipsychotic drugs and olderExpand
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