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Novel method for the isolation and characterisation of the putative prostatic stem cell
- R. Bhatt, M. Brown, +4 authors N. Clarke
- Biology, Medicine
- Cytometry. Part A : the journal of the…
- 1 August 2003
Prostate stem cells, responsible for the development, maturation, and function of the prostate, have been implicated in the aetiology of both benign prostate hyperplasia (BPH) and prostate cancer… Expand
MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome.
The structure and molecular signature of tumor-associated vasculature are distinct from those of the host tissue, offering an opportunity to selectively target the tumor blood vessels. To identify… Expand
T lymphocyte recruitment into renal cell carcinoma tissue: a role for chemokine receptors CXCR3, CXCR6, CCR5, and CCR6.
BACKGROUND Evidence suggests that some patients with renal cell carcinoma (RCC) respond to immunomodulatory therapies that activate T lymphocytes. A prerequisite for effective T cell therapy is… Expand
The natural history of postoperative renal function in patients undergoing ileal conduit diversion for cancer measured using serial isotopic glomerular filtration rate and 99m…
PURPOSE There is little consensus regarding long-term followup of renal function in patients who undergo urinary diversion. We established the usefulness of combined serial isotopic glomerular… Expand
Field evaluation of plant leaf extracts, oil and neem products against mango hopper (Amritodus atikinsoni Lethierry) and thrips (Scirtothrips mangiferae Hood).
The effect of perioperative distal vasal lavage on subsequent semen analysis after vasectomy: a prospective randomized controlled trial
Objective To determine the effect of perioperative distal vasal lavage with 50 mL of normal saline on subsequent time to azoospermia after vasectomy.
Radiofrequency-induced Thermo-chemotherapy Effect Versus a Second Course of Bacillus Calmette-Guérin or Institutional Standard in Patients with Recurrence of Non-muscle-invasive Bladder Cancer…
BACKGROUND There is no effective intravesical second-line therapy for non-muscle-invasive bladder cancer (NMIBC) when bacillus Calmette-Guérin (BCG) fails. OBJECTIVE To compare disease-free… Expand
Sorafenib Induces Therapeutic Response in a Patient with Metastatic Collecting Duct Carcinoma of Kidney
- J. Ansari, Arfeen Fatima, S. Chaudhri, R. Bhatt, M. Wallace, N. James
- Oncology Research and Treatment
- 19 January 2009
Background: Collecting duct carcinoma (CDC) is a rare and aggressive variant of renal cell carcinoma (RCC), which has poor response to cytokine therapy and chemotherapy. Introduction of tyrosine… Expand
Long-term proliferation of functional human NK cells, with conversion of CD56dim NK cells to a CD56bright phenotype, induced by carcinoma cells co-expressing 4-1BBL and IL-12
- A. Dowell, K. A. Oldham, R. Bhatt, S. Lee, P. Searle
- Chemistry, Medicine
- Cancer Immunology, Immunotherapy
- 1 May 2012
Abstract4-1BB ligation co-stimulates T cell activation, and agonistic antibodies have entered clinical trials. Natural killer (NK) cells also express 4-1BB following activation and are implicated in… Expand
Natural history of angiomyolipoma in lymphangioleiomyomatosis: implications for screening and surveillance
- Zhao W Yeoh, V. Navaratnam, R. Bhatt, I. McCafferty, R. Hubbard, S. Johnson
- Orphanet Journal of Rare Diseases
- 3 October 2014
BackgroundLAM is a rare disease of women categorised by lung cysts and lymphatic abnormalities. The disease occurs sporadically or associated with Tuberous Sclerosis Complex (TSC-LAM).… Expand