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Stoichiometry and turnover in single, functioning membrane protein complexes
Many essential cellular processes are carried out by complex biological machines located in the cell membrane. The bacterial flagellar motor is a large membrane-spanning protein complex thatExpand
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Bacterial flagellar motor.
  • Y. Sowa, R. Berry
  • Physics, Medicine
  • Quarterly reviews of biophysics
  • 1 May 2008
The bacterial flagellar motor is a reversible rotary nano-machine, about 45 nm in diameter, embedded in the bacterial cell envelope. It is powered by the flux of H+ or Na+ ions across the cytoplasmicExpand
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The maximum number of torque-generating units in the flagellar motor of Escherichia coli is at least 11.
Torque is generated in the rotary motor at the base of the bacterial flagellum by ion translocating stator units anchored to the peptidoglycan cell wall. Stator units are composed of the proteinsExpand
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Variable stoichiometry of the TatA component of the twin-arginine protein transport system observed by in vivo single-molecule imaging
The twin-arginine translocation (Tat) system transports folded proteins across the bacterial cytoplasmic membrane and the thylakoid membrane of plant chloroplasts. The essential components of the TatExpand
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Myxobacteria gliding motility requires cytoskeleton rotation powered by proton motive force
Myxococcus xanthus is a Gram-negative bacterium that glides over surfaces without the aid of flagella. Two motility systems are used for locomotion: social-motility, powered by the retraction of typeExpand
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Direct observation of steps in rotation of the bacterial flagellar motor
The bacterial flagellar motor is a rotary molecular machine that rotates the helical filaments that propel many species of swimming bacteria. The rotor is a set of rings up to 45 nm in diameter inExpand
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Composition, Formation, and Regulation of the Cytosolic C-ring, a Dynamic Component of the Type III Secretion Injectisome
The injectisome is a membrane complex through which some bacteria can inject effector proteins into host cells. This study reveals that the cytosolic C-ring structure has a dynamic relationship toExpand
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Torque-generating units of the flagellar motor of Escherichia coli have a high duty ratio
Rotation of the bacterial flagellar motor is driven by an ensemble of torque-generating units containing the proteins MotA and MotB. Here, by inducing expression of MotA in motA- cells underExpand
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Load-Dependent Assembly of the Bacterial Flagellar Motor
ABSTRACT It is becoming clear that the bacterial flagellar motor output is important not only for bacterial locomotion but also for mediating the transition from liquid to surface living. The outputExpand
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Rapid Chiral Assembly of Rigid DNA Building Blocks for Molecular Nanofabrication
Practical components for three-dimensional molecular nanofabrication must be simple to produce, stereopure, rigid, and adaptable. We report a family of DNA tetrahedra, less than 10 nanometers on aExpand
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