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Physiology of Na+/H+ Exchangers in the Male Reproductive Tract: Relevance for Male Fertility1

The expression pattern and physiological roles of SLC9 family members in the cells of the male reproductive tract as well as the molecular basis of H+ transport and its involvement in male reproductive potential are discussed.
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pH and male fertility: making sense on pH homeodynamics throughout the male reproductive tract

An up-to-date review on the distribution and role of the main intervenient on pH homeodynamics in the fluids throughout the male reproductive tract is presented and their relevance for the establishment of themale reproductive potential is discussed.
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Dose-dependent effects of caffeine in human Sertoli cells metabolism and oxidative profile: relevance for male fertility.

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Expression pattern of G protein-coupled receptor 30 in human seminiferous tubular cells.

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Carbonic anhydrases are involved in mitochondrial biogenesis and control the production of lactate by human Sertoli cells

This is the first report showing that CAs play an essential role in hSC metabolic dynamics, being involved in mitochondrial biogenesis and controlling lactate production.
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Aquaporin‐9 is expressed in rat Sertoli cells and interacts with the cystic fibrosis transmembrane conductance regulator

The results provide evidence that CFTR is involved in water homeostasis of the seminiferous tubular secretion and may open new insights on therapeutic targets to counteract subfertility/infertility in men with cystic fibrosis and mutations in the CFTR gene.
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Aquaporin-4 as a molecular partner of cystic fibrosis transmembrane conductance regulator in rat Sertoli cells.

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Effect of white tea (Camellia sinensis (L.)) extract in the glycolytic profile of Sertoli cell

WTEA extract altered the glycolytic profile of cultured SCs, stimulating lactate production and has an anti-apoptotic effect in the developing germ cells, which may be advantageous to improve male reproductive health.
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Hepatocyte and Sertoli Cell Aquaporins, Recent Advances and Research Trends

This review focuses on the most recent advances and research trends regarding the expression and modulation, as well as physiological and pathophysiological functions of AQPs in hepatocytes and Sertoli cells (SCs).
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Estradiol modulates Na+‐dependent HCO3− transporters altering intracellular pH and ion transport in human Sertoli cells: A role on male fertility?

High levels of estradiol (E2) are associated with low sperm production and quality and sertoli cells (SCs) are major targets for the hormonal signalling that regulates this complex process.
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