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P504S Immunohistochemical Detection in 405 Prostatic Specimens Including 376 18-Gauge Needle Biopsies
It is concluded that P504S has potential utility in the diagnosis of prostate cancer, including those treated by hormones and radiation, and is best used only in conjunction with strict light microscopic correlation and preferably with high molecular weight cytokeratin immunostaining. Expand
Prostate cancer diagnosed after initial biopsy with atypical small acinar proliferation suspicious for malignancy is similar to cancer found on initial biopsy.
An ASAP diagnosis represents undersampled cancer in at least 40% of cases and places men at risk of prostate cancer with similar clinicopathologic findings as in other men with cancer. Expand
BRAF mutations in aberrant crypt foci and hyperplastic polyposis.
It is shown that BRAF mutation status is heterogeneous among patients with multiple/large HPs and/or hyperplastic polyposis, suggesting differences in pathogenesis of HPs that indicate subsets within this phenotype. Expand
Rapid Intraoperative Immunohistochemical Evaluation of Sentinel Lymph Nodes for Metastatic Breast Carcinoma
Zymed RIHC is a sensitive method for detecting breast cancer metastases in SLNs and the speed, accuracy, and ease of interpretation of the test allow for recognition of micrometastases that might otherwise be undetectable by current methods of intraoperative evaluation. Expand
Rapid Immunohistochemistry for Cytokeratin in the Intraoperative Evaluation of Sentinel Lymph Nodes for Metastatic Breast Carcinoma
The rapid immunohistochemistry method was the least sensitive of all methods used to detect metastasis and would not be helpful in intraoperative assessment of sentinel lymph nodes in breast cancer patients due to its low sensitivity. Expand