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Cholinolytics in the treatment of anticholinesterase poisoning. V. The effectiveness of Parpanit with oximes in the treatment of organophosphorus poisoning.
- I. W. Coleman, G. Patton, R. Bannard
- Chemistry, Medicine
- Canadian journal of physiology and pharmacology
The effectiveness of Parpanit in the treatment of organophosphorus poisoning was examined and compared with that of atropine sulfate. The potency of Parpanit was assessed in the mouse, rat, hamster,… Expand
GUANIDINE COMPOUNDS. II. PREPARATION OF MONO- AND N,N-DI-ALKYLGUANIDINES
1-Guanyl-3,5-dimethylpyrazole nitrate is superior to S-methylisothiouronium sulphate as a reagent for preparation of simple salts of mono- and N,N-di-alkylguanidines from cyclohexylamine,… Expand
An improved gas—liquid chromatographic method for the analysis of bis(2-chloroethyl)sulfide collected from air by solvent entrapment
Cholinolytics in the treatment of anticholinesterase poisoning. II. Treatment of sarin poisoning with an oxime and various combinations of cholinolytic compounds.
- I. W. Coleman, P. E. Little, R. Bannard
- Chemistry, Medicine
- Canadian journal of biochemistry and physiology
- 1 June 1962
Thirty-four cholinolytic compounds were screened for protective activity in mice and rats exposed to sarin. All compounds were examined at a dosage of 50 μmoles/kg in the presence of 30 mg/kg of N-...
Adsorption of large lipophilic molecules with exclusion of small hydrophilic molecules by microencapsulated activated charcoal formed by coating with a polyethylene membrane
Activated charcoal microcapsules formed by coating charcoal granules with different concentrations of polyethylene were studied. Microcapsules containing lower polymer concentrations were found to be… Expand
Poly(vinylidene fluoride)- or poly(vinylidene chloride/vinyl chloride)-coated activated charcoal for the adsorption of large lipophilic molecules with exclusion of small hydrophilic molecules
Abstract Microencapsulated activated charcoal was prepared by coating charcoal granules (2-5 μm diameter) with different concentrations of poly (vinylidene fluoride) and of poly (vinylidene… Expand
PREPARATION OF ANTIDOTES FOR ANTICHOLINESTERASE POISONING: II. TERTIARY AND QUATERNARY SALTS OF PARPANIT AND PARPANIT ANALOGUES
A rapid, sensitive, gas-liquid chromatographic method for the analysis of bis(2-chloroethyl)sulfide collected from air in hydrocarbon solvents
Summary A rapid, sensitive gas chromatographic procedure for the analysis of mustard gas collected from air in hydrocarbon solvents has been developed to replace the 4-(4′-nitrobenzyl)pyridine… Expand
PREPARATION OF ANTIDOTES FOR ANTICHOLINESTERASE POISONING III. ESTERS OF 1-ARYLCYCLOALKANECARBOXYLIC ACIDS
In preceding papers of this series (1, 2) the preparation of several analogues of 5'diethylaminoethyl 1-phenylcyclopentanecarboxylate hydrochloride (Parpanit) and certain of their quaternary salts… Expand
Gas Chromatography of Some Polyamines on Three Porous Polymer Columns
Abstract The gas-solid chromatographic properties of some polyaminnes employing porous polymer bead packings are described. A review of the literature pertaining to the gas chromatography of amines… Expand