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Transcriptional Regulation of the Base Excision Repair Pathway by BRCA1*
Inactivation of the breast cancer susceptibility gene BRCA1 plays a significant role in the development of a subset of breast cancers, although the major tumor suppressor function of this geneExpand
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BRCA1 Localization to the Telomere and Its Loss from the Telomere in Response to DNA Damage*
BRCA1, a tumor suppressor, participates in DNA damage signaling and repair. Previously, we showed that BRCA1 overexpression caused inhibition of telomerase activity and telomere shortening in breastExpand
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Mechanisms of Orbital Floor Fractures: A Clinical, Experimental, and Theoretical Study
Purpose The purpose of this study was to investigate the two accepted mechanisms of the orbital blowout fracture (the hydraulic and the buckling theories) from a clinical, experimental, andExpand
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Economic evaluation of major knee surgery with recombinant activated factor VII in hemophilia patients with high titer inhibitors and advanced knee arthropathy: exploratory results via
ABSTRACT Objectives: People with severe hemophilia suffer from frequent intra-articular hemorrhages, leading to pain, swelling, reduced flexion, and arthropathy. Elective orthopedic surgery usingExpand
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Mechanisms of orbital floor fractures: a clinical, experimental, and theoretical study.
PURPOSE The purpose of this study was to investigate the two accepted mechanisms of the orbital blowout fracture (the hydraulic and the buckling theories) from a clinical, experimental, andExpand
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Fluorescent oligonucleotides can serve as suitable alternatives to radiolabeled oligonucleotides.
Prolonged exposure to radiation from radionuclei used in medical research can cause DNA damage and mutation, which lead to several diseases including cancer. Radioactivity-based experiments areExpand
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Mechanisms of Orbital Floor Fractures
Purpose: The purpose of this study was to investigate the two accepted mechanisms of the orbital blowout fracture (the hydraulic and the buckling theories) from a clinical, experimental, andExpand
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BRCA1 localization to the telomere and its loss upon DNA damage
BRCA1, a tumor suppressor, participates in DNA damage signaling and repair. Previously, we showed that BRCA1 over-expression caused inhibition of telomerase activity and telomere shortening in breastExpand