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Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression.
BACKGROUND Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of antidepressants combined with antipsychotics or mood stabilizers, relatively fewExpand
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A symptom rating scale for delirium
The authors present a 10-item clinician-rated symptom rating scale for delirium. Compared to demented, schizophrenic, and normal control groups, 20 delirious subjects scored significantly higher onExpand
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Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study
OBJECTIVE Few double-blind trials have compared longer-term efficacy and safety of medications for bipolar disorder. The authors report a 47-week comparison of olanzapine and divalproex. METHODExpand
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Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy.
BACKGROUND A 6-week double-blind, randomized, placebo-controlled trial was conducted to determine the efficacy of combined therapy with olanzapine and either valproate or lithium compared withExpand
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Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone
Background Few controlled studies have examined the use of atypical antipsychotic drugs for prevention of relapse in patients with bipolar I disorder. Aims To evaluate whether olanzapine plus eitherExpand
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Randomized, placebo-controlled trial of olanzapine as maintenance therapy in patients with bipolar I disorder responding to acute treatment with olanzapine.
OBJECTIVE In a placebo-controlled, double-blind study, the authors investigated the efficacy and safety of olanzapine as monotherapy in relapse prevention in bipolar I disorder. METHOD PatientsExpand
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Olanzapine versus divalproex in the treatment of acute mania.
OBJECTIVE The effects of olanzapine and divalproex for the treatment of mania were compared in a large randomized clinical trial. METHOD A 3-week, randomized, double-blind trial compared flexiblyExpand
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An excitement subscale of the Positive and Negative Syndrome Scale
BACKGROUND We sought to develop and validate an excitement subscale from the Positive and Negative Syndrome Scale (PANSS) to allow the investigation of mania-like excitement symptoms in clinicalExpand
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Olanzapine versus lithium in the maintenance treatment of bipolar disorder: a 12-month, randomized, double-blind, controlled clinical trial.
OBJECTIVE The authors compared the efficacy of olanzapine and lithium in the prevention of mood episode relapse/recurrence. METHOD Patients with a diagnosis of bipolar disorder (manic/mixed), aExpand
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A 12-week, double-blind comparison of olanzapine vs haloperidol in the treatment of acute mania.
BACKGROUND This randomized controlled trial compares the efficacy and safety of olanzapine vs haloperidol, as well as the quality of life of patients taking these drugs, in patients with bipolarExpand
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