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Substrate metabolism in the developing heart.
The developing heart undergoes a remarkable metabolic transformation as it adjusts to the higher-oxygen, extrauterine environment. During gestation, glycolysis and lactate oxidation constitute theExpand
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Pituitary Adenylate Cyclase Activating Polypeptide: A Neuropeptide with Potent Inotropic and Coronary Vasodilatory Effects in Neonatal Pig Hearts
ABSTRACT: Cardiac effects of the neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP) have not previously been reported. We investigated the influence of PACAP, vasoactiveExpand
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Complete unilateral leg duplication with ipsilateral renal agenesis
A case of a 5‐month‐old infant with complete duplication of the right leg and ipsilateral renal agenesis is presented. There was also a duplicated scrotum, posterior urethral valves withExpand
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Streamlining Fluid Pathways Lessens Flow Energy Dissipation: Relevance to Atriocavopulmonary Connections
Flow energy dissipation reduces cardiac efficiency, particularly in the Fontan-modified, single-ventricle heart. To provide insight into flow energetics relevant to Fontan-type anatomy, a simple,Expand
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Medtronic freestyle valves in right ventricular outflow tract reconstruction.
BACKGROUND Various pulmonary valve substitutes, with their inherent limitations, have been used in children and young adults. We chose the Medtronic Freestyle (Medtronics, Minneapolis, MN) valveExpand
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Accessory mitral valve tissue causing left ventricular outflow obstruction (two-dimensional echocardiographic diagnosis and surgical approach).
Accessory mitral valve tissue, a rare cause of left ventricular outflow tract obstruction, can be difficult to diagnose preoperatively and confusing even at surgery. The reported case illustrates howExpand
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Ventricular function and fatty acid metabolism in neonatal piglet heart.
Studies in which subcellular systems were used suggest that neonatal myocardium has a sharply limited capacity to metabolize fatty acids. The relationship of these findings to the intact heart wasExpand
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Intralobar pulmonary sequestration presenting as congestive heart failure in a neonate.
We recently evaluated a premature infant with intralobar pulmonary sequestration which presented with signs of CHF. The infant initially underwent ligation of a PDA but subsequently developedExpand
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Systematic-to-Pulmonary Collaterals: A Source of Flow Energy Loss in Fontan Physiology
Patients with Fontan-modified, single-ventricle heart frequently have systemic collaterals that increase pulmonary blood flow. Competitive flow from these auxiliary vessels can also elevate pulmonaryExpand
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