• Publications
  • Influence
Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells.
Efficient delivery of small interfering RNA (siRNA) remains a challenging task in RNA interference (RNAi) studies. In this study, we used chitosan-graft-polyethylenimine (CHI-g-PEI) copolymerExpand
  • 77
  • 4
Chitosan-graft-polyethylenimine as a gene carrier.
Chitosans have been proposed as biocompatible alternative cationic polymers that are suitable for non-viral delivery. However, the transfection efficiency of chitosan-DNA nanoparticles is still veryExpand
  • 239
  • 3
Galactosylated poly(ethylene glycol)-chitosan-graft-polyethylenimine as a gene carrier for hepatocyte-targeting.
Chitosan and chitosan derivatives have been proposed as alternative and biocompatible cationic polymers for non-viral gene delivery. However, the low transfection efficiency and low specificity ofExpand
  • 135
  • 3
Galactosylated chitosan-graft-polyethylenimine as a gene carrier for hepatocyte targeting
Chitosans have been proposed as alternative, biocompatible cationic polymers for nonviral gene delivery. However, the low transfection efficiency and low specificity of chitosan need to be addressedExpand
  • 119
  • 3
Degradable polyethylenimines as DNA and small interfering RNA carriers
  • D. Jere, H. Jiang, +5 authors C. Cho
  • Medicine, Materials Science
  • Expert opinion on drug delivery
  • 28 July 2009
Gene therapy is a powerful approach in the treatment of a wide range of both inherited and acquired diseases. Nonviral delivery systems have been proposed as safer alternatives to viral vectorsExpand
  • 94
  • 3
The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway.
RNA interference (RNAi) represents a promising new approach to the inhibition of gene expression in vitro and in vivo, and has therapeutic potential for human diseases. Efficient delivery of smallExpand
  • 106
  • 3
Mannosylated chitosan-graft-polyethylenimine as a gene carrier for Raw 264.7 cell targeting.
Gene transfer using non-viral vectors is a promising approach for the safe delivery of therapeutic genes. Among non-viral vectors, chitosans have been proposed as alternative, biocompatible cationicExpand
  • 88
  • 3
A biodegradable poly(ester amine) based on polycaprolactone and polyethylenimine as a gene carrier.
The aim of research was to develop and optimize delivery systems for plasmid DNA (pDNA) based on biodegradable polymers, in particular, poly(ester amine)s (PEAs), suitable for non-viral gene therapy.Expand
  • 159
  • 2
Biodegradable poly(ester amine) based on glycerol dimethacrylate and polyethylenimine as a gene carrier
Polyethylenimine (PEI) vectors are widely used in gene delivery because of their high transfection efficiency owing to a unique proton sponge effect. An increase in molecular weight increasesExpand
  • 57
  • 2
Capsaicin Regulates the NF-κB Pathway in Salivary Gland Inflammation
Salivary gland epithelial cells (SGEC) release several cytokines that play important roles in the inflammatory process. In this study, we examined whether capsaicin can modulate cytokine release inExpand
  • 19
  • 2