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The ENCODE (ENCyclopedia Of DNA Elements) Project
The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional elements in the human genome sequence. The pilot phase of the Project is focused on a specified 30 megabases (∼1%) of… Expand
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules.
- Andreas W. W. Ludwig, C. Hundhausen, +5 authors J. D. Becherer
- Medicine, Chemistry
- Combinatorial chemistry & high throughput…
- 28 February 2005
The transmembrane metzinkin-proteases of the ADAM (a disintegrin and a metalloproteinase)-family ADAM10 and ADAM 17 are both implicated in the ectodomain shedding of various cell surface molecules… Expand
A genetic linkage map for the zebrafish.
To facilitate molecular genetic analysis of vertebrate development, haploid genetics was used to construct a recombination map for the zebrafish Danio (Brachydanio) rerio. The map consists of 401… Expand
Membrane adsorption of endocrine disrupting compounds and pharmaceutically active compounds
Abstract Adsorption is one of the main mechanisms contributing to compound removal by membrane filtration, in addition to size exclusion and charge repulsion. In this study, the adsorption of 22… Expand
Formation of N-nitrosamines from eleven disinfection treatments of seven different surface waters.
Formation of nine N-nitrosamines has been investigated when seven different source waters representing various qualities were each treated with eleven bench-scale disinfection processes, without… Expand
The rejection of endocrine disrupting and pharmaceutically active compounds by NF and RO membranes as a function of compound and water matrix properties
Abstract This study examined the rejection of 22 endocrine disrupting compounds (EDCs) and pharmaceutically active compounds (PhAC) from raw and 5-μm filtered Lake Ontario water, membrane bioreactor… Expand
Inactivation of Adenovirus Types 2, 5, and 41 in Drinking Water by UV Light, Free Chlorine, and Monochloramine
A bench-scale study was conducted to determine the inactivation of adenovirus (Ad) types 2, 5, and 41 by ultraviolet (UV) light, chlorine, and monochloramine. The motivation for this study was to… Expand
RAGE Ligation Affects T Cell Activation and Controls T Cell Differentiation1
- Y. Chen, E. Akirav, +11 authors K. Herold
- Biology, Medicine
- The Journal of Immunology
- 15 September 2008
The pattern recognition receptor, RAGE, has been shown to be involved in adaptive immune responses but its role on the components of these responses is not well understood. We have studied the… Expand
Comparative analysis of chlorine dioxide, free chlorine and chloramines on bacterial water quality in model distribution systems
Drinking water utilities may be required to change disinfectant to improve water quality and meet more stringent disinfection regulations. This research was conducted to assess and compares chlorin...
Engineered biofiltration for ultrafiltration fouling mitigation and disinfection by-product precursor control
A pilot-scale study was conducted to evaluate the impact of several biofiltration enhancement strategies in terms of organic removal to reduce disinfection by-product (DBP) formation potential and… Expand