• Publications
  • Influence
Coevolution of hosts and parasites.
The authors conclude that such associations may be responsible for much of the genetic diversity found within natural populations, from blood group polymorphisms to protein polymorphisms in general. Expand
Heterogeneities in the transmission of infectious agents: implications for the design of control programs.
From an analysis of the distributions of measures of transmission rates among hosts, we identify an empirical relationship suggesting that, typically, 20% of the host population contributes at leastExpand
Processes influencing the distribution of parasite numbers within host populations with special emphasis on parasite-induced host mortalities.
It is shown that, for certain types of host-parasite associations, convex curves of mean parasite abundance in relation to age (age-intensity curves), concomitant with a decline in the degree of dispersion in the older age, classes of hosts, may be evidence of the induction in host mortality by parasite infection. Expand
Epidemiology and genetics in the coevolution of parasites and hosts
  • R. May, R. Anderson
  • Biology, Medicine
  • Proceedings of the Royal Society of London…
  • 22 October 1983
The way in which earlier studies fit into a wider scheme is reviewed, offering some new ideas about host-parasite coevolution and one central conclusion is that ‘successful’ parasites need not necessarily evolve to be harmless. Expand
Chaos, persistence, and evolution of strain structure in antigenically diverse infectious agents.
The effects of selection by host immune responses on transmission dynamics was analyzed in a broad class of antigenically diverse pathogens, finding that strain structure is unstable, varying in a manner that is either cyclical or chaotic. Expand
The invasion, persistence and spread of infectious diseases within animal and plant communities.
  • R. Anderson, R. May
  • Biology, Medicine
  • Philosophical transactions of the Royal Society…
  • 15 December 1986
The frequency distribution of the number of different sexual partners per unit of time within homosexual communities is shown to be of central importance with respect to future trends in the incidence of AIDS and to have far-reaching implications for the structure and stability of ecological communities. Expand
Helminth infections of humans: mathematical models, population dynamics, and control.
The chapter provides a brief description of observed epidemiological patterns, concentrating on age-prevalence and age-intensity trends and a historical review of the development of the mathematical models of helminth infections. Expand
A preliminary study of the transmission dynamics of the human immunodeficiency virus (HIV), the causative agent of AIDS.
Preliminary attempts to formulate simple mathematical models of the transmission dynamics of HIV infection in homosexual communities are described, and the influence of variation in the incubation period and heterogeneity in sexual activity is assessed. Expand
Vancomycin-resistant enterococci in intensive-care hospital settings: transmission dynamics, persistence, and the impact of infection control programs.
Hand washing and staff cohorting are the most powerful control measures although their efficacy depends on the magnitude of R0, and endemicity of VRE was stabilized despite infection control measures, by the constant introduction of colonized patients. Expand
HIV infection and reproductive health in teenage women orphaned and made vulnerable by AIDS in Zimbabwe
OVCs (overall), maternal orphans and young women with an infected parent were more likely to have received no secondary school education and to have started sex and married, which, in turn, were associated with poor reproductive health. Expand