Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study.
Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults: The Adverse Childhood Experiences (ACE) Study.
The enduring effects of abuse and related adverse experiences in childhood
- R. Anda, V. Felitti, W. Giles
- Psychology, MedicineEuropean Archives of Psychiatry and Clinical…
- 1 April 2006
The graded relationship of the ACE score to 18 different outcomes in multiple domains theoretically parallels the cumulative exposure of the developing brain to the stress response with resulting impairment in multiple brain structures and functions.
Childhood abuse, neglect, and household dysfunction and the risk of illicit drug use: the adverse childhood experiences study.
- S. Dube, V. Felitti, M. Dong, D. Chapman, W. Giles, R. Anda
- Medicine, PsychologyPediatrics
- 1 March 2003
The persistent graded relationship between the ACE score and initiation of drug use for 4 successive birth cohorts dating back to 1900 suggests that the effects of adverse childhood experiences transcend secular changes such as increased availability of drugs, social attitudes toward drugs, and recent massive expenditures and public information campaigns to prevent drug use.
Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span: findings from the Adverse Childhood Experiences Study.
- S. Dube, R. Anda, V. Felitti, D. Chapman, D. Williamson, W. Giles
- Psychology, MedicineJAMA
- 26 December 2001
A powerful graded relationship exists between adverse childhood experiences and risk of attempted suicide throughout the life span, and alcoholism, depressed affect, and illicit drug use, which are strongly associated with such experiences, appear to partially mediate this relationship.
The interrelatedness of multiple forms of childhood abuse, neglect, and household dysfunction.
Adverse childhood experiences and the risk of depressive disorders in adulthood.
Long-term consequences of childhood sexual abuse by gender of victim.
Relationship between multiple forms of childhood maltreatment and adult mental health in community respondents: results from the adverse childhood experiences study.
- V. Edwards, G. Holden, V. Felitti, R. Anda
- Psychology, MedicineAmerican Journal of Psychiatry
- 1 August 2003
OBJECTIVE This study examined the prevalence of a history of various combinations of childhood maltreatment types (physical abuse, sexual abuse, and witnessing of maternal battering) among adult…
Adverse childhood experiences, alcoholic parents, and later risk of alcoholism and depression.
Depression among adult children of alcoholics appears to be largely, if not solely, due to the greater likelihood of having had adverse childhood experiences in a home with alcohol-abusing parents.