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Relationship between 1,25-dihydroxyvitamin-D, calcium and uric acid in urinary stone formers.
The results show that urinary UA and 1,25-dihydroxyvitamin-D in serum co-influence Ca stone formation, and they suggest that there is an increased sensitivity to 1, 25-(OH)2- D in formers of Ca stones. Expand
Vascular Endothelial-cadherin plays a role in regulating the Norrin-FZD4 pathway and can cause Familial Exududative- vitroretinopathy (FEVR).
FEVR is a genetic disorder that causes abnormal vascularization of the retina, which can lead to retinal detachment and blindness. Mutations in the genes encoding Norrin, LRP5, FZD4 and TSPAN12 canExpand