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The effect of intrapartum epidural analgesia on nulliparous labor: a randomized, controlled, prospective trial.
OBJECTIVE Our purpose was to determine the effect of epidural analgesia on nulliparous labor and delivery. STUDY DESIGN Normal term nulliparous women in early spontaneous labor were randomized toExpand
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The Cpx proteins of Escherichia coli K12. Immunologic detection of the chromosomal cpxA gene product.
Previous studies described lacZ'- and cat'-'cpxA fusion genes whose expression restored to normal all the phenotypic defects associated with cpxA mutations (Albin, R., and Silverman, P. M. (1984)Expand
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SCH 48973: a potent, broad-spectrum, antienterovirus compound.
SCH 48973 is a novel molecule with potent, selective, antienterovirus activity. In assays of the cytopathic effect against five picornaviruses, SCH 48973 had antiviral activity (50% inhibitoryExpand
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SCH 43478 and analogs: in vitro activity and in vivo efficacy of novel agents for herpesvirus type 2.
SCH 43478 and analogs are a class of non-nucleoside antiviral agents that have potent and selective activity against herpes simplex virus type 2 (HSV-2). The IC50 for these compounds in plaqueExpand
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The Epstein-Barr virus BZLF1 gene product activates the human immunodeficiency virus type 1 5' long terminal repeat.
The Epstein-Barr virus immediate-early gene product BZLF1 transactivates the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR). The BZLF1 gene product caused an 18-fold increaseExpand
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Development of Antiviral Agents for Picornavirus Infections
The discovery and development of antiviral agents for the treatment of picornavirus infections have been the focus of extensive research for more than 50 years. This chapter discusses theExpand
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Strategies for discovering antiviral agents from natural products.
Publisher Summary This chapter discusses the strategies for discovering antiviral agents from natural products. The goal of a screening assay is to discover an agent that acts on a specific viralExpand
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Identification of the Escherichia coli K-12 cpxA locus as a single gene: construction and analysis of biologically-active cpxA gene fusions
SummaryIn the accompanying communication we showed that a 2 kb EcoRI-BamHI restriction fragment from the pfkA-rha interval of the Escherichia coli K-12 chromosome fully complemented a chromosomalExpand
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Physical and genetic structure of the glpK-cpxA interval of the Escherichia coli K-12 chromosome
SummaryMutations at the cpxA locus of Escherichia coli K-12 affect cellular processes that are not otherwise related. We have now determined the physical and genetic structure of the E. coliExpand
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Compositions analgesiques a base d'antagonistes du recepteur nmda et chlorure de benzalkonium
L'invention concerne des compositions pharmaceutiques composees de taux efficaces d'antagonistes du recepteur NMDA et d'un agent de conservation pour l'administration d'analgesiques etExpand