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Biological Role of Pituitary Estrogen Receptors ERα and ERβ on Progesterone Receptor Expression and Action and on Gonadotropin and Prolactin Secretion in the Rat
TLDR
The finding that activation of ERβ with its selective DPN agonist had an estrogenic effect on IR-PR nuclei, but not on GnRH self-priming, a characteristic ERα-mediated effect of E, suggests that the biological action of E at the pituitary may involve both isoforms of ER. Expand
Interactions between N-methyl-D-aspartate, nitric oxide and serotonin in the control of prolactin secretion in prepubertal male rats.
TLDR
It is concluded that endogenous glutamate stimulates prolactin release and that NO might have a pivotal role in the mechanisms involved in the control of PRL release, inhibiting the release of dopamine and modulating the effects of NMDA and 5-HT. Expand
Tamoxifen but Not Other Selective Estrogen Receptor Modulators Antagonizes Estrogen Actions on Luteinizing Hormone Secretion while Inducing Gonadotropin-Releasing Hormone Self-Priming in the Rat
TLDR
Data from this study indicated that, in contrast to the general antagonistic effect of the tested SERMs, TX seemed to display both selective agonist and antagonist activity at the gonadotrope level and on GnRH self-priming of LH secretion respectively. Expand
Balano‐Preputial Separation as an External Sign of Puberty in the Rat: Correlation with Histologic Testicular Data/Balano‐praeputial‐Trennung als ein äußeres Zeichen der Pubertät für die Ratte:
TLDR
Data indicate that the advancement in BPS induced by pituitary grafts was not in keeping with an equivalent enhancement of testicular development. Expand
Effects of neonatal estrogen administration on rat testis development with particular reference to Sertoli cells.
TLDR
An ultrastructural and morphometric study of the testes in 15, 22, 45, and 90-day-old neonatally estrogenized rats was performed, revealing decreased testicular and tubular volumes as well as decreased mean tubular diameters in the estrogenized animals. Expand
Testicular serotonin is related to mast cells but not to Leydig cells in the rat.
TLDR
The data suggest that mast cells are a major source of serotonin in the rat testis, in spite of the elimination of Leydig cells. Expand
RU486-treated rats show endocrine and morphological responses to therapies analogous to responses of women with polycystic ovary syndrome treated with similar therapies.
TLDR
The fundamental adequacy of using the RU486-treated rat as a PCO model is established as endocrine and morphologic alterations comparable to those observed in women with PCO and an ovulatory response to combined treatment with FSH and LH are evaluated. Expand
Mechanisms of inhibitory action of kainic acid on prolactin secretion in male rats.
TLDR
The inhibitory action of KA is independent of the age of the animal, the gonadal status and the prevailing PRL levels, and the action is probably mediated by an increase in dopamine secretion and by a direct effect at the pituitary level. Expand
Gonadotropin-secreting cells in ovariectomized rats treated with different oestrogen receptor ligands: a modulatory role for ERbeta in the gonadotrope?
TLDR
It is suggested that the structural reorganization of the cytoplasmic organelles provided by oestrogen, and the shrinkage of the ovariectomy-induced hypertrophy of gonadotropes, which precedes the expression of PR, are evoked by ERalpha and modulated, in a ying-yang fashion, by ERbeta. Expand
The fate of corpora lutea in the cyclic golden hamster.
TLDR
Data indicate that, in contrast to its close relatives (e.g., the rat), structural luteolysis in the hamster is independent of the apoptotic inducing lutenolytic hormones. Expand
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