• Publications
  • Influence
Hepatic glutathione and nitric oxide are critical for hepatic insulin-sensitizing substance action.
We tested the hypothesis that hepatic nitric oxide (NO) and glutathione (GSH) are involved in the synthesis of a putative hormone referred to as hepatic insulin-sensitizing substance HISS. InsulinExpand
  • 82
  • 3
  • PDF
Smart cities software architectures: a survey
TLDR
The smart cities concept arises from the need to manage, automate, optimize and explore all aspects of a city that could be improved. Expand
  • 82
  • 3
Meal-induced insulin sensitization in conscious and anaesthetized rat models comparing liquid mixed meal with glucose and sucrose.
We have recently shown that meal-induced insulin sensitization (MIS) occurs after feeding and decreases progressively to insignificance after 24 h of fasting and is caused by action of a hepaticExpand
  • 29
  • 3
  • PDF
Brazilian smart cities: using a maturity model to measure and compare inequality in cities
TLDR
This paper compares some of the Brazilian capital indicators and presents a maturity model called br-SCMM (Brazilian Smart City Maturity Model) developed to allow extracted indicators of public databases may be used to assist city managers. Expand
  • 26
  • 3
Postprandial but not fasting insulin resistance is an early identifier of dysmetabolism in overweight subjects.
The dynamic response to insulin is highly potentiated after meal ingestion, and this meal-induced insulin sensitization (MIS) in healthy subjects is dependent on cholinergic mechanisms. The mainExpand
  • 5
  • 2
Meal-induced insulin sensitization and its parasympathetic regulation in humans.
In animal studies, the whole-body glucose disposal effect of insulin is low in the fasted state or after atropine infusion, but doubles after a meal, consistent with the hepatic insulin-sensitizingExpand
  • 29
  • 1
Carvedilol action is dependent on endogenous production of nitric oxide.
BACKGROUND Carvedilol is known to be an adrenoreceptor blocker and free radical scavenger, used in hypertension and cardiac failure. However, its therapeutic actions cannot be fully explained byExpand
  • 31
  • 1
Loss of postprandial insulin sensitization during aging.
With aging, there is a decrease in parasympathetic nervous activity. Since the hepatic parasympathetic nerves (HPNs) are essential to the disposal of nutrients, through the hepatic insulinExpand
  • 19
  • 1
  • PDF
Hepatic parasympathetic role in insulin resistance on an animal model of hypertension.
The hepatic insulin sensitizing substance (HISS) pathway, which includes the hepatic parasympathetic nerves and hepatic nitric oxide (HNO), has been shown to be crucial to the action of insulin onExpand
  • 15
  • 1
Efficacy of carvedilol in reversing hypertension induced by chronic intermittent hypoxia in rats.
Animal models of chronic intermittent hypoxia (CIH) mimic the hypertension observed in patients with obstructive sleep apnoea. Antihypertensive drugs were applied to these animal models to addressExpand
  • 11
  • 1