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Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors
Flavonoids have recently aroused considerable interest because of their broad pharmacological activity. In fact, flavonoids have been reported to have antiviral, antiallergic, antiplatelet,… Expand
L-Propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector
L-Propionylcarnitine, a propionyl ester of L-carnitine, increases the intracellular pool of L-carnitine. It exhibits a high affinity for the enzyme carnitine acetyltransferase (CAT) and, thus, is… Expand
Antioxidant activity and protective effect on DNA cleavage of extracts from Cistus incanus L. and Cistus monspeliensis L.
The genus Cistus includes many typical species of Mediterranean flora; Cistus species are used as antidiarrheics, as general remedies for treatment of various skin diseases in folk medicine and as… Expand
In vitro evaluation of idebenone-loaded solid lipid nanoparticles for drug delivery to the brain
- L. Montenegro, A. Campisi, +4 authors G. Puglisi
- Chemistry, Medicine
- Drug development and industrial pharmacy
- 12 May 2011
Context: Solid lipid nanoparticles (SLN) are regarded as interesting drug delivery systems and their preparation techniques have gained a great deal of attention. Objective: To evaluate the… Expand
Propofol Attenuates Peroxynitrite-mediated DNA Damage and Apoptosis in Cultured Astrocytes: An Alternative Protective Mechanism
Background:The concentration of peroxynitrite in the brain increases after central nervous system injuries. The authors hypothesized that propofol, because of its particular chemical structure,… Expand
Nitric oxide-related toxicity in cultured astrocytes: effect of Bacopa monniera.
- A. Russo, F. Borrelli, A. Campisi, R. Acquaviva, G. Raciti, A. Vanella
- Biology, Medicine
- Life sciences
- 8 August 2003
There is growing evidence that high concentrations of nitric oxide (NO), generated by activated astrocytes, might be involved in a variety of neurodegenerative diseases, such as Alzheimer's disease,… Expand
Antiproliferative effect of oleuropein in prostate cell lines.
- R. Acquaviva, C. Di Giacomo, +7 authors L. Vanella
- Biology, Medicine
- International journal of oncology
- 1 July 2012
Currently, there is increasing interest in the in vivo protective effects of natural antioxidants found in dietary plants against oxidative damage caused by free radical species. Oxidative stress has… Expand
Thyroglobulin binding and TSH regulation of the RHL-1 subunit of the asialoglycoprotein receptor in rat thyroid.
- F. Pacifico, D. Liguoro, R. Acquaviva, S. Formisano, E. Consiglio
- Medicine, Biology
- 1 May 1999
The ability of asialo-thyroglobulin to bind the thyroid RHL-1 subunit of the asialoglycoprotein receptor has been investigated. Ligand blot assays show that the recombinant carbohydrate recognition… Expand
Red Orange Extract: Effect on DNA Cleavage
ABSTRACT: Red oranges are characterized by high levels of anthocyanins, with a high content of other antioxidant compounds such as flavones, hydroxycinnamic acids, and ascorbic acid. In this work, we… Expand
Effect of Treatment with Cyanidin-3-O-β-D-Glucoside on Rat Ischemic/Reperfusion Brain Damage
- C. Di Giacomo, R. Acquaviva, +6 authors F. Galvano
- Evidence-based complementary and alternative…
- 13 September 2012
This study investigated the effect of cyanidin-3-O-β-glucoside on an experimental model of partial/transient cerebral ischemia in the rats in order to verify the effectiveness of both pre- and… Expand