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Central nervous system involvement in childhood systemic lupus erythematosus.
The records of 37 patients with systemic lupus erythematosus (SLE) followed at The Children's Hospital of Philadelphia between 1968 and 1978 were reviewed for evidence of central nervous system (CNS)… Expand
Pulmonary manifestations of juvenile rheumatoid arthritis. A report of eight cases and review.
- B. H. Athreya, R. A. Doughty, M. Bookspan, H. Schumacher, E. M. Sewell, J. Chatten
- Clinics in chest medicine
- 1 September 1980
Pleuropulmonary disease was seen in 4 per cent of patients with juvenile rheumatoid arthritis. Roentgenographic abnormalities seen in association with juvenile rheumatoid arthritis include: transient… Expand
Neonatal presentation of I-cell disease.
Two patients are described in whom the diagnosis of I-cell disease was established in early infancy. These patients lacked many of the clinical and radiographic features described in other children… Expand
Detection of antibodies to the recombinant P39 protein of Borrelia burgdorferi using enzyme immunoassay and immunoblotting.
- P. Fawcett, C. Rosé, K. Gibney, C. Chase, B. Kiehl, R. A. Doughty
- Biology, Medicine
- The Journal of rheumatology
- 1 April 1993
The diagnostic value of serologic tests using the recombinant P39 protein of Borrelia burgdorferi was compared with that of tests prepared from a whole spirochete antigen source. Immunoassays (ELISA… Expand
Childhood Lyme arthritis: experience in an endemic area.
We report 25 children with oligoarticular arthritis associated with Lyme disease. There were 16 boys (male/female ratio 1.8:1); ages ranged from 2 to 15 years. Thirteen (52%) children had no history… Expand
Utility of rheumatoid factor in the diagnosis of juvenile rheumatoid arthritis.
Rheumatoid factor is commonly used by clinicians to assess children with possible juvenile rheumatoid arthritis. To assess its usefulness, we reviewed the case histories of patients in whom latex… Expand
The Overdiagnosis of Lyme Disease in Children Residing in an Endemic Area
The medical records of 227 children ages 1 to 19 years referred to the Lyme disease pediatric clinic over a 32-month period since May 1990 were reviewed. Clinico-serologic criteria for a positive… Expand
Pediatric Lyme arthritis: clinical spectrum and outcome.
- C. Rosé, P. Fawcett, S. Eppes, J. D. Klein, K. Gibney, R. A. Doughty
- Journal of pediatric orthopedics
- 1 March 1994
A cohort of children with Lyme arthritis was used to evaluate the clinical and serologic profile of the disease. During a 42-month period (June 1989 to December 1991), 44 patients (13 girls and 31… Expand
Frequency and specificity of antibodies that crossreact with Borrelia burgdorferi antigens.
The frequency and specificity of antibodies that bind antigens of Borrelia burgdorferi in sera from 200 individuals with no evidence of past or current Lyme disease was determined. Sera were tested… Expand
Esophageal motor abnormalities in children and adolescents with scleroderma and mixed connective tissue disease.
To determine the frequency and nature of esophageal motor abnormalities in children and adolescents with scleroderma syndromes and mixed connective tissue disease, esophageal manometry was performed… Expand