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GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues.
TLDR
These data provide an extensive analysis of GAPDH mRNA expression in human tissues and confirm previous reports of the marked variability ofGAPDH expression between tissue types. Expand
A novel inhibitory prostanoid receptor in piglet saphenous vein.
TLDR
The piglet saphenous vein contains TP-receptors mediating smooth muscle contraction, and a PGE2-specific (EP) receptor mediating relaxation, providing strong evidence for the presence of inhibitory EP-receptor blocking drugs. Expand
COMPARISON OF THE ACTIONS OF U‐46619, A PROSTAGLANDIN H2‐ANALOGUE, WITH THOSE OF PROSTAGLANDIN H2 AND THROMBOXANE A2 ON SOME ISOLATED SMOOTH MUSCLE PREPARATIONS
TLDR
It is suggested that U‐46619 is a selective TxA2‐mimetic and that it should therefore be a valuable tool in the study of the actions of TXA2. Expand
EP4 prostanoid receptor‐mediated vasodilatation of human middle cerebral arteries
TLDR
The presence of prostanoid EP4 receptors mediating PGE2 vasodilatation of human middle cerebral artery is characterised and IP receptor agonists mediating relaxation and TP receptor mediating contraction were functionally demonstrated. Expand
GR159897, a potent non-peptide antagonist at tachykinin NK2 receptors.
TLDR
GR159897 is a novel, highly potent and selective non-peptide antagonist at tachykinin NK2 receptors that should be a useful tool for studying the physiological and pathophysiological role of tachyKinin NK 2 receptor activation. Expand
Salmeterol, a novel, long‐acting β2‐adrenoceptor agonist: characterization of pharmacological activity in vitro and in vivo
TLDR
Salmeterol is a potent and selective β2‐adrenoceptor agonist with a remarkably long duration of action in isolated superfused airways smooth muscle and causes persistent bronchodilatation in vivo, in the guinea‐pig, when administered by the inhaled route. Expand
Characterization of the PGE receptor subtype mediating inhibition of superoxide production in human neutrophils
TLDR
The hypothesis that adenosine 3′:5′‐cyclic monophosphate (cyclic AMP) is the second messenger mediating the inhibition of the neutrophil by prostaglandin (PG)E2.1 is tested. Expand
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