R W Yakaitis

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Factors that may influence energy requirements for ventricular defibrillation include the duration of fibrillation and the mode of resuscitation. The present study assesses the effect of these influences on the energy needed for defibrillation. Dogs were anesthetized, and arterial blood pressure and Lead II of the ECG were continuously recorded. Ventricular(More)
Two new catecholamines, dopamine and dobutamine, have found widespread use for cardiovascular support. The relative efficacy of these drugs in aiding resuscitation from cardiopulmonary arrest is unknown. Dogs were subjected to either asphyxial or fibrillatory cardiac arrest. Resuscitation was attempted with artificial ventilation, closed chest cardiac(More)
To determine the relative importance of the alpha and beta adrenergic effects of epinephrine in resuscitation, 32 dogs were studied in four groups. Group A (alpha blocked) received phenoxybenzamine, 70 mg/kg; group B (beta blocked), propranolol 5 mg/kg; group C (alpha and beta blocked) both drugs; and group D (control), no drug. After this treatment and 5(More)
Successful resuscitation from cardiac arrest in the asphyxiated dog model has been ascribed to the use of artificial ventilation, closed chest cardiac massage, and administration of a vasopressor. Controversy remains over whether the most commonly employed vasopressor, epinephrine, exerts its effects primarily by elevating diastolic pressure and(More)
Previous studies have suggested that early postoperative hypozemia may be due to a reduction of functional residual capacity (FRC) during anesthesia and surgery. Positive end-expiratory pressure (PEEP) has been recommended as a means of maintaining FRC and improving arterial oxygenation. Fifteen selected patients undergoing peripheral surgical procedures(More)
Clinical impressions about the problem of defibrillation during states of acid-base imbalance and hypoxia have been influenced by studies involving the effect of these derangements on the ventricular fibrillation threshold. Based on body weight, energy requirements for defibrillation in normal dogs were compared to requirements in dogs subjected to commonly(More)