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  • R. W. Gülch, R. Baumann, R. Jacob
  • 1979
Action potentials were measured in hypertrophied rat myocardium by means of glass microelectrodes. Left ventricular hypertrophy was induced by experimental chronic coarctation of one renal artery without contralateral nephrectomy. The action potentials of the hypertrophied myocardium exhibit a marked prolongation without any significant changes in the(More)
  • R W Gülch
  • 1994
Based on the physiological principles of the muscular force-velocity concept, this paper deals with the special problems associated with determining and interpreting force-velocity relations of muscles in situ particularly in humans. In the strict sense, instead of force-velocity relations merely torque-angular velocity relations of a joint can be measured(More)
Length-tension diagrams and force-velocity relations of isolated cat papillary muscles were measured under strictly stationary conditions: any analysis of isometric mechanograms was carried out only in stable isometric beats; each measurement in beats under any condition different from the isometric one was determined in the very first contraction after a(More)
On the basis of theoretical considerations and experimental data this study deals with the functional consequences of structural dilatation, particularly in view of Linzbach's concept of chronic heart failure (34-38). After a short review of the literature, a theoretical analysis of the relationship between stroke volume and ventricular inner radius is(More)
On the basis of two different models of damped release experiments, the passive component of the all-over shortening velocity throughout an abrupt unloading of cardiac muscle is calculated by treating the muscle functionally as a non-linear spring. It can be shown that: 1. in a time range where normally data for constructing force-velocity relations are(More)
The effects of an 8-week unilateral contract-relax (CR) stretching training program (passive stretch after isometric contraction) on muscular performance were investigated in a group of 16 athletes. The flexibility, maximum torque and angular position as well as contraction work in movements of the knee joint were determined before training and after 4 and(More)
In the isotonically beating cat papillary muscle, a sudden augmentation of the preload initiates a visco-elastic strain retardation, in the course of which the preparations show a marked increase in their isotonic mechanogram amplitudes. It is preceded in the first seconds by a short-term decline. These effects correspond well with the phenomena of stress(More)
  • Dipl.-Phys. B. Dierberger, M. Brändle, R. W. Gülch, R. Jacob
  • 1991
A methodological approach based on Frank's pressure-volume (P-V) diagram and model calculations for analyzing the determinants of stroke volume (SV) under conditions of altered ventricular geometrical configuration is discussed with respect to the underlying geometrical models. The approach is generalized in the sense that alterations in myocardial(More)
End-systolic length-tension relationships were measured on ultrathin isolated heart preparations of rat (mean diameter +/- S.D. = 96 microns +/- 45 microns). Independent of contractile state being changed by variation in extracellular Ca++-concentration no unique end-systolic length-tension relation was found when varying pre- and afterload over a wide(More)